Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 183 aminokiseline , a molekulska težina 20.826 Da .[ 7]
10 20 30 40 50
MRAAYLFLLF LPAGLLAQGQ YDLDPLPPFP DHVQYTHYSD QIDNPDYYDY
QEVTPRPSEE QFQFQSQQQV QQEVIPAPTP EPGNAELEPT EPGPLDCREE
QYPCTRLYSI HRPCKQCLNE VCFYSLRRVY VINKEICVRT VCAHEELLRA
DLCRDKFSKC GVMASSGLCQ SVAASCARSC GSC
^ a b c GRCh38: Ensembl release 89: ENSG00000117122 - Ensembl , maj 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060572 - Ensembl , maj 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Faraco J, Bashir M, Rosenbloom J, Francke U (Jun 1995). "Characterization of the human gene for microfibril-associated glycoprotein (MFAP2), assignment to chromosome 1p36.1-p35, and linkage to D1S170". Genomics . 25 (3): 630–7. doi :10.1016/0888-7543(95)80004-6 . PMID 7759096 .
^ a b "Entrez Gene: MFAP2 microfibrillar-associated protein 2" .
^ "UniProt, P55001" (jezik: eng.). Pristupljeno 30. 11. 2021 .CS1 održavanje: nepoznati jezik (link )
Dopunska literatura
uredi
Gibson MA, Hughes JL, Fanning JC, Cleary EG (1986). "The major antigen of elastin-associated microfibrils is a 31-kDa glycoprotein" . J. Biol. Chem . 261 (24): 11429–36. doi :10.1016/S0021-9258(18)67403-4 . PMID 3015971 .
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 .
Brown-Augsburger P, Broekelmann T, Rosenbloom J, Mecham RP (1996). "Functional domains on elastin and microfibril-associated glycoprotein involved in elastic fibre assembly" . Biochem. J . 318 (1): 149–55. doi :10.1042/bj3180149 . PMC 1217601 . PMID 8761465 .
Finnis ML, Gibson MA (1997). "Microfibril-associated glycoprotein-1 (MAGP-1) binds to the pepsin-resistant domain of the alpha3(VI) chain of type VI collagen" . J. Biol. Chem . 272 (36): 22817–23. doi :10.1074/jbc.272.36.22817 . PMID 9278443 .
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 .
Fujimoto N, Tajima S, Ishibashi A (2000). "Expression of microfibril-associated glycoprotein-1 (MAGP-1) in human epidermal keratinocytes". Arch. Dermatol. Res . 292 (1): 21–6. doi :10.1007/PL00007456 . PMID 10664011 . S2CID 36505268 .
Trask BC, Broekelmann T, Ritty TM, et al. (2001). "Posttranslational modifications of microfibril associated glycoprotein-1 (MAGP-1)". Biochemistry . 40 (14): 4372–80. CiteSeerX 10.1.1.721.7743 . doi :10.1021/bi002738z . PMID 11284693 .
Jensen SA, Reinhardt DP, Gibson MA, Weiss AS (2001). "Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1" . J. Biol. Chem . 276 (43): 39661–6. doi :10.1074/jbc.M104533200 . PMID 11481325 .
Reinboth B, Hanssen E, Cleary EG, Gibson MA (2002). "Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1" . J. Biol. Chem . 277 (6): 3950–7. doi :10.1074/jbc.M109540200 . PMID 11723132 .
Segade F, Trask BC, Broekelmann TJ, et al. (2002). "Identification of a matrix-binding domain in MAGP1 and MAGP2 and intracellular localization of alternative splice forms" . J. Biol. Chem . 277 (13): 11050–7. doi :10.1074/jbc.M110347200 . PMID 11796718 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Werneck CC, Trask BC, Broekelmann TJ, et al. (2004). "Identification of a major microfibril-associated glycoprotein-1-binding domain in fibrillin-2" . J. Biol. Chem . 279 (22): 23045–51. doi :10.1074/jbc.M402656200 . PMID 15044481 .
Clarke AW, Weiss AS (2004). "Microfibril-associated glycoprotein-1 binding to tropoelastin: multiple binding sites and the role of divalent cations" . Eur. J. Biochem . 271 (14): 3085–90. doi :10.1111/j.1432-1033.2004.04246.x . PMID 15233806 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
Miyamoto A, Lau R, Hein PW, et al. (2006). "Microfibrillar proteins MAGP-1 and MAGP-2 induce Notch1 extracellular domain dissociation and receptor activation" . J. Biol. Chem . 281 (15): 10089–97. doi :10.1074/jbc.M600298200 . PMID 16492672 .
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1" . Nature . 441 (7091): 315–21. Bibcode :2006Natur.441..315G . doi :10.1038/nature04727 . PMID 16710414 .