Protein cinkovog prsta 695 jest protein koji je kod ljudi kodiran genom ZNF695 sa hromosoma 1.[3]
ZNF695 |
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Identifikatori |
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Aliasi | ZNF695 |
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Vanjski ID-jevi | OMIM: 616348 HomoloGene: 130710 GeneCards: ZNF695 |
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Ontologija gena |
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Molekularna funkcija | • vezivanje iona metala • nucleic acid binding • GO:0001948, GO:0016582 vezivanje za proteine • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
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Ćelijska komponenta | • intracellular anatomical structure • jedro
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Biološki proces | • GO:0009373 regulation of transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
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Izvori:Amigo / QuickGO |
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Ortolozi |
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Vrste | Čovjek | Miš |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNK) | | |
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RefSeq (bjelančevina) | | |
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Lokacija (UCSC) | Chr 1: 246.95 – 247.01 Mb | n/a |
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PubMed pretraga | [2] | n/a |
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Wikipodaci |
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Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 515 aminokiselina, a molekulska težina 60.149 Da.[4]
10 | | 20 | | 30 | | 40 | | 50 |
MGLLAFRDVA | | LEFSPEEWEC | | LDPAQRSLYR | | DVMLENYRNL | | ISLGEDSFNM |
QFLFHSLAMS | | KPELIICLEA | | RKEPWNVNTE | | KTARHSVLSS | | YLTEDILPEQ |
GLQVSFQKVM | | LRRYERCCLE | | KLRLRNDWEI | | VGEWKGQKAS | | YNGLDLCSAT |
THSKNFQCNK | | CVKGFSKFAN | | LNKCKISHTG | | EKPFKCKECG | | NVSCMSLIMT |
QQQRIHIGEN | | PYQCKKCGKA | | FNECSCFTDC | | KRIHVGEKHC | | KCEECNNIFK |
SCSSLAVVEK | | NHTEKKTYRC | | EECGKAFNLC | | SVLTKHKKIH | | TGEKPYKCEE |
CGKSFKLFPY | | LTQHKRIHSR | | EKPYKCEECG | | KVFKLLSYLT | | QHRRIHTGEK |
TFRCEECGKA | | FNQSSHLTEH | | RRIHTGEKPY | | KCEECGKAFT | | WFSYLIQHKR |
IHTGQKPYKC | | EECGKAFTWF | | SYLTQHKRIH | | TGEKPYKCDE | | CGKAFNWFSY |
LTNHKRIHTG | | EKPYKCEECG | | KAFGQSSHLS | | KHKTIHTREK | | PYKCEECGKA |
FNHSAQLAVH | | EKTHT |
Dopunska literatura
uredi
- Takahashi T, Yamahsita S, Matsuda Y, Kishino T, Nakajima T, Kushima R, Kato K, Igaki H, Tachimori Y, Osugi H, Nagino M, Ushijima T (2015). "ZNF695 methylation predicts a response of esophageal squamous cell carcinoma to definitive chemoradiotherapy". J. Cancer Res. Clin. Oncol. 141 (3): 453–63. doi:10.1007/s00432-014-1841-x. PMID 25273507. S2CID 6120553.
- Juarez-Mendez S, Zentella-Dehesa A, Villegas-Ruiz V, Perez-Gonzalez OA, Salcedo M, Lopez-Romero R, Roman-Basaure E, Lazos-Ochoa M, Montes de Oca-Fuentes VE, Vazquez-Ortiz G, Moreno J (2013). "Splice variants of zinc finger protein 695 mRNA associated to ovarian cancer". J Ovarian Res. 6 (1): 61. doi:10.1186/1757-2215-6-61. PMC 3847372. PMID 24007497.