ZNF687

Protein cinkovog prsta 687 je cinkov prst koji je kod ljudi kodiran genom ZNF687 sa hromosoma 1.

ZNF687
Identifikatori
Aliasi	ZNF687
Vanjski ID-jevi	OMIM: 610568 MGI: 1925516 HomoloGene: 10827 GeneCards: ZNF687
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek) Bend 1q21.3 Početak 151,281,618 bp Kraj 151,292,176 bp
Lokacija gena (miš) Hrom. Hromosom 3 (miš) Bend 3|3 F2.1 Početak 95,006,590 bp Kraj 95,015,448 bp
Ontologija gena Molekularna funkcija • vezivanje iona metala • vezivanje sa DNK • GO:0001948, GO:0016582 vezivanje za proteine • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • jedro • citoplazma • nukleoplazma • citosol Biološki proces • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	57592	78266
Ensembl	ENSG00000143373	ENSMUSG00000019338
UniProt	Q8N1G0	Q9D2D7
RefSeq (mRNK)	NM_001304763 NM_001304764 NM_020832	NM_030074 NM_001357863
RefSeq (bjelančevina)	NP_001291692 NP_001291693 NP_065883	NP_084350 NP_001344792
Lokacija (UCSC)	Chr 1: 151.28 – 151.29 Mb	Chr 3: 95.01 – 95.02 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 1 237 aminokiselina, a molekulska težina 129.529 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MGDMKTPDFD		DLLAAFDIPD		IDANEAIHSG		PEENEGPGGP		GKPEPGVGSE
SEDTAAASAG		DGPGVPAQAS		DHGLPPPDIS		VVSVIVKNTV		CPEQSEALAG
GSAGDGAQAA		GVTKEGPVGP		HRMQNGFGSP		EPSLPGTPHS		PAPPSGGTWK
EKGMEGKTPL		DLFAHFGPEP		GDHSDPLPPS		APSPTREGAL		TPPPFPSSFE
LAQENGPGMQ		PPVSSPPLGA		LKQESCSPHH		PQVLAQQGSG		SSPKATDIPA
SASPPPVAGV		PFFKQSPGHQ		SPLASPKVPV		CQPLKEEDDD		EGPVDKSSPG
SPQSPSSGAE		AADEDSNDSP		ASSSSRPLKV		RIKTIKTSCG		NITRTVTQVP
SDPDPPAPLA		EGAFLAEASL		LKLSPATPTS		EGPKVVSVQL		GDGTRLKGTV
LPVATIQNAS		TAMLMAASVA		RKAVVLPGGT		ATSPKMIAKN		VLGLVPQALP
KADGRAGLGT		GGQKVNGASV		VMVQPSKTAT		GPSTGGGTVI		SRTQSSLVEA
FNKILNSKNL		LPAYRPNLSP		PAEAGLALPP		TGYRCLECGD		AFSLEKSLAR
HYDRRSMRIE		VTCNHCARRL		VFFNKCSLLL		HAREHKDKGL		VMQCSHLVMR
PVALDQMVGQ		PDITPLLPVA		VPPVSGPLAL		PALGKGEGAI		TSSAITTVAA
EAPVLPLSTE		PPAAPATSAY		TCFRCLECKE		QCRDKAGMAA		HFQQLGPPAP
GATSNVCPTC		PMMLPNRCSF		SAHQRMHKNR		PPHVCPECGG		NFLQANFQTH
LREACLHVSR		RVGYRCPSCS		VVFGGVNSIK		SHIQTSHCEV		FHKCPICPMA
FKSGPSAHAH		LYSQHPSFQT		QQAKLIYKCA		MCDTVFTHKP		LLSSHFDQHL
LPQRVSVFKC		PSCPLLFAQK		RTMLEHLKNT		HQSGRLEETA		GKGAGGALLT
PKTEPEELAV		SQGGAAPATE		ESSSSSEEEE		VPSSPEPPRP		AKRPRRELGS
KGLKGGGGGP		GGWTCGLCHS		WFPERDEYVA		HMKKEHGKSV		KKFPCRLCER
SFCSAPSLRR		HVRVNHEGIK		RVYPCRYCTE		GKRTFSSRLI		LEKHVQVRHG
LQLGAQSPGR		GTTLARGSSA		RAQGPGRKRR		QSSDSCSEEP		DSTTPPAKSP
RGGPGSGGHG		PLRYRSSSST		EQSLMMGLRV		EDGAQQCLDC		GLCFASPGSL
SRHRFISHKK		RRGVGKASAL		GLGDGEEEAP		PSRSDPDGGD		SPLPASGGPL
TCKVCGKSCD		SPLNLKTHFR		THGMAFIRAR		QGAVGDN

Dopunska literatura

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.