ZNF648

Protein cinkovog prsta 436 jest protein koji je kod ljudi kodiran genom ZNF436 sa hromosoma 1.

ZNF648
Identifikatori
Aliasi	ZNF648
Vanjski ID-jevi	MGI: 2685049 HomoloGene: 18996 GeneCards: ZNF648
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek) Bend 1q25.3 Početak 182,054,570 bp Kraj 182,061,712 bp
Lokacija gena (miš) Hrom. Hromosom 1 (miš) Bend 1|1 G3 Početak 154,076,933 bp Kraj 154,081,435 bp
Ontologija gena Molekularna funkcija • vezivanje sa DNK • vezivanje iona metala • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity Ćelijska komponenta • jedro Biološki proces • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	127665	100503355
Ensembl	ENSG00000179930	ENSMUSG00000066797
UniProt	Q5T619	D3Z0W3
RefSeq (mRNK)	NM_001009992	NM_001204908
RefSeq (bjelančevina)	NP_001009992	NP_001191837
Lokacija (UCSC)	Chr 1: 182.05 – 182.06 Mb	Chr 1: 154.08 – 154.08 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 470 aminokiselina, a molekulska težina 54.277 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAATLLMAGS		QAPVTFEDMA		MYLTREEWRP		LDAAQRDLYR		DVMQENYGNV
VSLDFEIRSE		NEVNPKQEIS		EDVQFGTTSE		RPAENAEENP		ESEEGFESGD
RSERQWGDLT		AEEWVSYPLQ		PVTDLLVHKE		VHTGIRYHIC		SHCGKAFSQI
SDLNRHQKTH		TGDRPYKCYE		CGKGFSRSSH		LIQHQRTHTG		ERPYDCNECG
KSFGRSSHLI		QHQTIHTGEK		PHKCNECGKS		FCRLSHLIQH		QRTHSGEKPY
ECEECGKSFS		RSSHLAQHQR		THTGEKPYEC		NECGRGFSER		SDLIKHYRVH
TGERPYKCDE		CGKNFSQNSD		LVRHRRAHTG		EKPYHCNECG		ENFSRISHLV
QHQRTHTGEK		PYECNACGKS		FSRSSHLITH		QKIHTGEKPY		ECNECWRSFG
ERSDLIKHQR		THTGEKPYEC		VQCGKGFTQS		SNLITHQRVH		TGEKPYECTE
CEKSFSRSSA		LIKHKRVHTD

Također pogledajte

• ZNF692

Dopunska literatura

• Li Y, Du X, Li F, et al. (2007). "A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE". Mol. Biol. Rep. 33 (4): 287–94. doi:10.1007/s11033-006-9019-5. PMID 17089209. S2CID 13591444.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
• Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.