Protein cinkovog prsta 510 je protein koji je kod ljudi kodiran genom ZNF510 .[3]
ZNF510 Identifikatori Aliasi ZNF510 Vanjski ID-jevi HomoloGene : 88832 GeneCards : ZNF510 Ontologija gena Molekularna funkcija • vezivanje sa DNK • vezivanje iona metala • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • intracellular anatomical structure • jedro Biološki proces • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi Vrste Čovjek Miš Entrez Ensembl UniProt RefSeq (mRNK) RefSeq (bjelančevina) Lokacija (UCSC) Chr 9: 96.75 – 96.78 Mb n/a PubMed pretraga[2] n/a Wikipodaci
Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 683 aminokiseline , а molekulska težina 79.142 Da .[4]
10 20 30 40 50 MSPHPEAITD CVTLNTVGQL AEGGYPLRFS TLFQEQQKMN ISQASVSFKD VTIEFTQEEW QQMAPVQKNL YRDVMLENYS NLVSVGYCCF KPEVIFKLEQ GEEPWFSEEE FSNQSHPKDY RGDDLIKQNK KIKDKHLEQA ICINNKTLTT EEEKVLGKPF TLHVAAVAST KMSCKCNSWE VNLQSISEFI INNRNYSTKK IGCGNVCENS PFKINFEKTQ TGEKFYEHNK NMKALNYNEN LPKHPKFQTL EQAFECNKIG KAFNDKANCV KHNSSHTGET SSKDDEFRKN CDKKTLFDHR RTGTGKKHLH LNQCGKSFEK STVEEYNKLN MGIKHYELNP SGNNFNRKAH LTDPQTAVIE ENPLVSNDRT QTWVKSSEYH ENKKSYQTSV HRVRRRSHSM MKPYKCNECG KSFCQKGHLI QHQRTHTGEK PFECSECGKT FSQKSHLSTH QRIHTAEKPY KCNECGKTFV QKSTLRGHQR IHTGEKPYEC SECGKTFVQK STLRDHHRIH TGEKSFQCNQ CGKTFGQKSN LRIHQRTHTG EKTYQCNECE KSFWRKDHLI QHQKTHTGEK PFKCNECGKT FARTSTLRVH QRIHTGEKPF KCNECGKKFV RKAILSDHQR IHTGEKPFQC NKCGKTFGQK SNLRIHQRTH SGEKSYECNE YGKLCKKSTL SLYQKIQGEG NPY
|cinkovog prstaOvaj gen kodira člana porodice proteina krupel C2H2 tipa cinkov prst . Kodirani protein eksprimiran je u nekoliko tipova ćelija raka i može biti biomarker za ranu dijagnozu ovih karcinoma .
Dopunska literatura
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Lei SF, Yang TL, Tan LJ, Chen XD, Guo Y, Guo YF, Zhang L, Liu XG, Yan H, Pan F, Zhang ZX, Peng YM, Zhou Q, He LN, Zhu XZ, Cheng J, Liu YZ, Papasian CJ, Deng HW (2009). "Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci" . Hum. Genet . 125 (1): 1–9. doi :10.1007/s00439-008-0590-9 . PMC 2730511 PMID 19030899 . 
