ZBED6

ZBED6
Identifikatori
Aliasi	ZBED6
Vanjski ID-jevi	OMIM: 613512 MGI: 3828086 HomoloGene: 130066 GeneCards: ZBED6
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	203,854,999 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	133,589,056 bp
Ontologija gena
Molekularna funkcija	• vezivanje sa DNK; • protein dimerization activity; • vezivanje iona metala; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • RNA polymerase II transcription regulatory region sequence-specific DNA binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• Jedarce; • jedro;
Biološki proces	• GO:0045996 negative regulation of transcription, DNA-templated; • GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	100381270
	667118
	ENSG00000257315
	ENSMUSG00000094410
	P86452
	D2EAC2
	NM_001174108; NM_001395895
	NM_001166552; NM_001395904
	NP_001167579
	NP_001160024; NP_001382833
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Cinkov prst sa BED-tipom 6 jest protein koji je kod ljudi kodiran genom ZBED6 sa hromosoma 1.^[5]

Aminokiselinska sekvenca

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000257315 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000094410 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger, BED-type containing 6". Pristupljeno 15. 3. 2012.
^ "UniProt, P86452" (jezik: en.). Pristupljeno 8. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L (Dec 2009). O'Rahilly S (ured.). "ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth". PLOS Biology. 7 (12): e1000256. doi:10.1371/journal.pbio.1000256. PMC 2780926. PMID 20016685.
Butter F, Kappei D, Buchholz F, Vermeulen M, Mann M (Apr 2010). "A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth". EMBO Reports. 11 (4): 305–11. doi:10.1038/embor.2010.6. PMC 2854606. PMID 20134481.
Andersson L (2010). "Studying phenotypic evolution in domestic animals: a walk in the footsteps of Charles Darwin". Cold Spring Harbor Symposia on Quantitative Biology. 74: 319–25. doi:10.1101/sqb.2009.74.039. PMID 20375320.