RNK-vezujući protein 6 jest protein koji je kod ljudi kodiran genom RBM6 sa hromosoma 3.[5][6] RBM6 ortolozi[7] identificirani su kod svih sisara za koje su dostupni potpuni podaci o genomu.

RBM6
Identifikatori
AliasiRBM6
Vanjski ID-jeviOMIM: 606886 MGI: 1338037 HomoloGene: 31336 GeneCards: RBM6
Lokacija gena (čovjek)
Hromosom 3 (čovjek)
Hrom.Hromosom 3 (čovjek)[1]
Hromosom 3 (čovjek)
Genomska lokacija za RBM6
Genomska lokacija za RBM6
Bend3p21.31Početak49,940,007 bp[1]
Kraj50,100,045 bp[1]
Lokacija gena (miš)
Hromosom 9 (miš)
Hrom.Hromosom 9 (miš)[2]
Hromosom 9 (miš)
Genomska lokacija za RBM6
Genomska lokacija za RBM6
Bend9|9 F1Početak107,650,758 bp[2]
Kraj107,750,436 bp[2]
Ontologija gena
Molekularna funkcija vezivanje sa DNK
GO:0001948, GO:0016582 vezivanje za proteine
nucleic acid binding
vezivanje sa RNK
Ćelijska komponenta jedro
Biološki proces GO:0033168, GO:0036404, GO:1902360 RNA processing
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_001167582
NM_005777
NM_001349190
NM_001349191
NM_001349192

NM_001349193
NM_001349194

NM_011251
NM_029169

RefSeq (bjelančevina)
NP_001161054
NP_005768
NP_001336119
NP_001336120
NP_001336121

NP_001336122
NP_001336123

n/a

Lokacija (UCSC)Chr 3: 49.94 – 50.1 MbChr 9: 107.65 – 107.75 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 1.123 aminokiseline, а molekulska težina 128.644 Da.[8].

1020304050
MWGDSRPANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHSGNFPGR
DSLPFDFQGHSGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDF
SSSDFQSRDSSQLDFRGRDIHSGDFRDREGPPMDYRGGDGTSMDYRGREA
PHMNYRDRDAHAVDFRGRDAPPSDFRGRGTYDLDFRGRDGSHADFRGRDL
SDLDFRAREQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGSGTTDLDFRDR
DTPHSDFRGRHRSRTDQDFRGREMGSCMEFKDREMPPVDPNILDYIQPST
QDREHSGMNVNRREESTHDHTIERPAFGIQKGEFEHSETREGETQGVAFE
HESPADFQNSQSPVQDQDKSQLSGREEQSSDAGLFKEEGGLDFLGRQDTD
YRSMEYRDVDHRLPGSQMFGYGQSKSFPEGKTARDAQRDLQDQDYRTGPS
EEKPSRLIRLSGVPEDATKEEILNAFRTPDGMPVKNLQLKEYNTGYDYGY
VCVEFSLLEDAIGCMEANQGTLMIQDKEVTLEYVSSLDFWYCKRCKANIG
GHRSSCSFCKNPREVTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADK
EPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETR
QDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHT
YGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHS
DHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYY
DPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKR
DGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNP
LIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLT
DWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYL
ERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDID
TSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSK
RQSNETYRDAVRRVMFARYKELD

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000004534 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032582 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH (Aug 1999). "A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3". Eur J Hum Genet. 7 (4): 478–86. doi:10.1038/sj.ejhg.5200334. PMID 10352938.
  6. ^ "Entrez Gene: RBM6 RNA binding motif protein 6".
  7. ^ "OrthoMaM phylogenetic marker: RBM6 coding sequence". Arhivirano s originala, 3. 3. 2016. Pristupljeno 5. 11. 2021.
  8. ^ "UniProt, P78332" (jezik: engleski). Pristupljeno 5. 11. 2021.

Dopunska literatura

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Vanjski linkovi

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RBM6 detalji ljudskog genoma u UCSC Genome Browser.