Proenzim fosfatiduilserin-dekarboksilaza jest enzim koji je kod ljudi kodiran genom PISD sa hromosoma 22.[5][6]

PISD
Identifikatori
AliasiPISD
Vanjski ID-jeviOMIM: 612770 MGI: 2445114 HomoloGene: 81653 GeneCards: PISD
Lokacija gena (čovjek)
Hromosom 22 (čovjek)
Hrom.Hromosom 22 (čovjek)[1]
Hromosom 22 (čovjek)
Genomska lokacija za PISD
Genomska lokacija za PISD
Bend22q12.2Početak31,618,491 bp[1]
Kraj31,662,221 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za PISD
Genomska lokacija za PISD
Bend5|5 B1Početak32,893,645 bp[2]
Kraj32,942,990 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija carboxy-lyase activity
lyase activity
phosphatidylserine decarboxylase activity
Ćelijska komponenta integral component of membrane
mitochondrial inner membrane
membrana
mitohondrija
jedro
integral component of mitochondrial inner membrane
Biološki proces lipid metabolism
phospholipid biosynthetic process
phosphatidylethanolamine biosynthetic process
protein autoprocessing
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_014338
NM_001326411
NM_001326412
NM_001326413
NM_001326414

NM_001326415
NM_001326416
NM_001326417
NM_001326418
NM_001326419
NM_001326420
NM_001326421
NM_178022

NM_177298
NM_001347332

RefSeq (bjelančevina)
NP_001313340
NP_001313341
NP_001313342
NP_001313343
NP_001313344

NP_001313345
NP_001313346
NP_001313347
NP_001313348
NP_001313349
NP_001313350
NP_055153
NP_821141

NP_001334261
NP_796272

Lokacija (UCSC)Chr 22: 31.62 – 31.66 MbChr 5: 32.89 – 32.94 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 409 aminokiselina, a molekulska težina 46.672 Da[6]

1020304050
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDA
RKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERELEKLGLEIPP
KLAGHWEVALYKSVPTRLLSRAWGRLNQVELPHWLRRPVYSLYIWTFGVN
MKEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGRILNFGQV
KNCEVEQVKGVTYSLESFLGPRMCTEDLPFPPAASCDSFKNQLVTREGNE
LYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFC
HNERVVLTGDWKHGFFSLTAVGATNVGSIRIYFDRDLHTNSPRHSKGSYN
DFSFVTHTNREGVPMRKGEHLGEFNLGSTIVLIFEAPKDFNFQLKTGQKI
RFGEALGSL

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000241878 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023452 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
  6. ^ a b "Entrez Gene: PISD phosphatidylserine decarboxylase".

Dopunska literatura

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Vanjski linkovi

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