RNK-vezujući protein NOB1 je protein koji je kod ljudi kodiran genom NOB1 .[ 5] [ 6]
Hartz (2010) je mapirala gen NOB1 u hromosomu, regija 16q22.1, na osnovu poravnanja sekvence NOB1 (GenBank AB026125) sa genomskom sekvencom (GRCh37).
Aminokiselinska sekvenca
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Dužina polipeptidnog lanca je 412 aminokiselina , a molekulska težina 46.675 Da [ 7]
Simboli
10 20 30 40 50 MAPVEHVVAD AGAFLRHAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP YELRFKEPLP EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPQKV KVSSSIQHPE TPLHISGFHL PYKPKPPQET EKGHSACEPE NLEFSSFMFW RNPLPNIDHE LQELLIDRGE DVPSEEEEEE ENGFEDRKDD SDDDGGGWIT PSNIKQIQQE LEQCDVPEDV RVGCLTTDFA MQNVLLQMGL HVLAVNGMLI REARSYILRC HGCFKTTSDM SRVFCSHCGN KTLKKVSVTV SDDGTLHMHF SRNPKVLNPR GLRYSLPTPK GGKYAINPHL TEDQRFPQLR LSQKARQKTN VFAPDYIAGV SPFVENDISS RSATLQVRDS TLGAGRRRLN PNASRKKFVK KR
^ a b c GRCh38: Ensembl release 89: ENSG00000141101 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003848 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Zhang Y, Ni J, Zhou G, Yuan J, Ren W, Shan Y, Tang W, Yu L, Zhao S (Sep 2005). "Cloning, expression and characterization of the human NOB1 gene". Mol Biol Rep . 32 (3): 185–9. doi :10.1007/s11033-005-3141-7 . PMID 16172919 . S2CID 12892523 . ^ "Entrez Gene: NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)" .^ "UniProt, Q9ULX3" . Pristupljeno 8. 7. 2021 .
Dopunska literatura
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Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation" . Genome Res . 14 (7): 1315–23. doi :10.1101/gr.2122004 . PMC 442147 PMID 15231747 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Fatica A, Oeffinger M, Dlakić M, Tollervey D (2003). "Nob1p is required for cleavage of the 3' end of 18S rRNA" . Mol. Cell. Biol . 23 (5): 1798–807. doi :10.1128/MCB.23.5.1798-1807.2003 . PMC 151717 PMID 12588997 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 PMID 12477932 . Daniele A, Altruda F, Ferrone M, et al. (1992). "Cloning and expression of a new human polypeptide which regulates protein phosphorylation in Escherichia coli". Mol. Cell. Biochem . 107 (2): 87–94. doi :10.1007/bf00225511 . PMID 1791827 . S2CID 25617287 . 
