Dermatopontin

Vjerovatno ATP-ovisna RNK-helikaza DDX59 jest enzim koji je kod ljudi kodiran genom DDX59 sa hromosoma 1.

Dermatopontin
Identifikatori
Aliasi	DPT
Vanjski ID-jevi	OMIM: 125597 MGI: 1928392 HomoloGene: 1458 GeneCards: DPT
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek) Bend 1q24.2 Početak 168,695,468 bp Kraj 168,729,206 bp
Lokacija gena (miš) Hrom. Hromosom 1 (miš) Bend 1|1 H2.2 Početak 164,624,213 bp Kraj 164,651,835 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • extracellular matrix structural constituent • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • GO:0005578 Vanćelijski matriks • extracellular region • Egzosom • Vanćelijsko • collagen-containing extracellular matrix Biološki proces • Ćelijska adhezija • negative regulation of cell population proliferation • collagen fibril organization Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	1805	56429
Ensembl	ENSG00000143196	ENSMUSG00000026574
UniProt	Q07507	Q9QZZ6
RefSeq (mRNK)	NM_001937	NM_019759
RefSeq (bjelančevina)	NP_001928	NP_062733
Lokacija (UCSC)	Chr 1: 168.7 – 168.73 Mb	Chr 1: 164.62 – 164.65 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 619 aminokiselina, a molekulska težina Da. 68 810

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MFVPRSLKIK		RNANDDGKSC		VAKIIKPDPE		DLQLDKSRDV		PVDAVATEAA
TIDRHISESC		PFPSPGGQLA		EVHSVSPEQG		AKDSHPSEEP		VKSFSKTQRW
AEPGEPICVV		CGRYGEYICD		KTDEDVCSLE		CKAKHLLQVK		EKEEKSKLSN
PQKADSEPES		PLNASYVYKE		HPFILNLQED		QIENLKQQLG		ILVQGQEVTR
PIIDFEHCSL		PEVLNHNLKK		SGYEVPTPIQ		MQMIPVGLLG		RDILASADTG
SGKTAAFLLP		VIMRALFESK		TPSALILTPT		RELAIQIERQ		AKELMSGLPR
MKTVLLVGGL		PLPPQLYRLQ		QHVKVIIATP		GRLLDIIKQS		SVELCGVKIV
VVDEADTMLK		MGFQQQVLDI		LENIPNDCQT		ILVSATIPTS		IEQLASQLLH
NPVRIITGEK		NLPCANVRQI		ILWVEDPAKK		KKLFEILNDK		KLFKPPVLVF
VDCKLGADLL		SEAVQKITGL		KSISIHSEKS		QIERKNILKG		LLEGDYEVVV
STGVLGRGLD		LISVRLVVNF		DMPSSMDEYV		HQIGRVGRLG		QNGTAITFIN
NNSKRLFWDI		AKRVKPTGSI		LPPQLLNSPY		LHDQKRKEQQ		KDKQTQNDLV
TGANLMDIIR		KHDKSNSQK

Dopunska literatura

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.