Ekto-ADP-riboziltransferaza 3 jest enzim koji je kod ljudi kodiran genom ART3 sa hromosoma 4.[5][6]

ART3
Identifikatori
AliasiART3
Vanjski ID-jeviOMIM: 603086 MGI: 1202729 HomoloGene: 911 GeneCards: ART3
Lokacija gena (čovjek)
Hromosom 4 (čovjek)
Hrom.Hromosom 4 (čovjek)[1]
Hromosom 4 (čovjek)
Genomska lokacija za ART3
Genomska lokacija za ART3
Bend4q21.1|4p15.1-p14Početak76,011,184 bp[1]
Kraj76,112,802 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za ART3
Genomska lokacija za ART3
Bend5 E2|5 46.54 cMPočetak92,479,686 bp[2]
Kraj92,562,487 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija NAD+ ADP-ribosyltransferase activity
glycosyltransferase activity
GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity
aktivnost sa transferazom
Ćelijska komponenta anchored component of membrane
membrana
integral component of plasma membrane
Egzosom
extracellular region
ćelijska membrana
intrinsic component of plasma membrane
Biološki proces protein ADP-ribosylation
C-terminal protein lipidation
peptidyl-arginine ADP-ribosylation
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001130016
NM_001130017
NM_001179

NM_181728
NM_001310664
NM_001310665
NM_001370591

RefSeq (bjelančevina)
NP_001123488
NP_001123489
NP_001170
NP_001364102
NP_001364103

NP_001364104
NP_001364105
NP_001364106
NP_001364107
NP_001364108
NP_001364109
NP_001364110
NP_001364111
NP_001364112
NP_001364113
NP_001364114

NP_001297593
NP_001297594
NP_859417
NP_001357520

Lokacija (UCSC)Chr 4: 76.01 – 76.11 MbChr 5: 92.48 – 92.56 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 389 aminokiselina, а molekulska težina 43.923 Da.[7]

1020304050
MKTGHFEIVTMLLATMILVDIFQVKAEVLDMADNAFDDEYLKCTDRMEIK
YVPQLLKEEKASHQQLDTVWENAKAKWAARKTQIFLPMNFKDNHGIALMA
YISEAQEQTPFYHLFSEAVKMAGQSREDYIYGFQFKAFHFYLTRALQLLR
KPCEASSKTVVYRTSQGTSFTFGGLNQARFGHFTLAYSAKPQAANDQLTV
LSIYTCLGVDIENFLDKESERITLIPLNEVFQVSQEGAGNNLILQSINKT
CSHYECAFLGGLKTENCIENLEYFQPIYVYNPGEKNQKLEDHSEKNWKLE
DHGEKNQKLEDHGVKILEPTQIPGMKIPEPFPLPEDKSQGNINNPTPGPV
PVPGPKSHPSASSGKLLLPQFGMVIILISVSAINLFVAL

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000156219 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034842 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Koch-Nolte F, Haag F, Braren R, Kühl M, Hoovers J, Balasubramanian S, Bazan F, Thiele HG (1997). "Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins". Genomics. 39 (3): 370–6. doi:10.1006/geno.1996.4520. PMID 9119374.
  6. ^ "Entrez Gene: ART3 ADP-ribosyltransferase 3".
  7. ^ "UniProt, Q13508" (jezik: engleski). Pristupljeno 22. 10. 2021.

Dopunska literatura

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Vanjski linkovi

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