Protein cinkovog prsta 76 jest protein koji je kod ljudi kodiran genom ZNF76.[5][6]

ZNF76
Identifikatori
AliasiZNF76
Vanjski ID-jeviOMIM: 194549 MGI: 2687278 HomoloGene: 2569 GeneCards: ZNF76
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za ZNF76
Genomska lokacija za ZNF76
Bend6p21.31Početak35,258,909 bp[1]
Kraj35,295,985 bp[1]
Lokacija gena (miš)
Hromosom 17 (miš)
Hrom.Hromosom 17 (miš)[2]
Hromosom 17 (miš)
Genomska lokacija za ZNF76
Genomska lokacija za ZNF76
Bend17|17 A3.3Početak28,396,103 bp[2]
Kraj28,424,860 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija vezivanje iona metala
vezivanje sa DNK
nucleic acid binding
GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
sequence-specific DNA binding
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta jedro
Biološki proces GO:0009373 regulation of transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
transcription, DNA-templated
regulation of transcription by RNA polymerase III
transcription by RNA polymerase II
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001292032
NM_003427

NM_172617
NM_001357995

RefSeq (bjelančevina)

NP_001278961
NP_003418

NP_766205
NP_001344924

Lokacija (UCSC)Chr 6: 35.26 – 35.3 MbChr 17: 28.4 – 28.42 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 570 aminokiselina, а molekulska težina 61.831 Da.[7]

1020304050
MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQ
KEALSFEDGQPVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHH
PVAVPSESTILAVQTEVGLEDLAAEDDEGFSADAVVALEQYASKVLHDSQ
IPRNGKGQQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFP
SCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHT
GERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSAT
NYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSTC
GKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPK
RPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQQVSLSPED
LQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADGTQTQPVT
IITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQLEEQQTLEEAINVA
TAAMQQGAVTLETTVSESGC

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000065029 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024220 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Dec 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID 1427894.
  6. ^ "Entrez Gene: ZNF76 zinc finger protein 76 (expressed in testis)".
  7. ^ "UniProt, P36508" (jezik: engleski). Pristupljeno 4. 10. 2021.

Dopunska literatura

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