ZNF532

Cinkoprstni protein 532 je protein koji je kod ljudi kodiran genom ZNF532.

ZNF532
Identifikatori
Aliasi	ZNF532
Vanjski ID-jevi	MGI: 3036282 HomoloGene: 10053 GeneCards: ZNF532
Lokacija gena (čovjek) Hrom. Hromosom 18 (čovjek) Bend 18q21.32 Početak 58,862,600 bp Kraj 58,986,480 bp
Lokacija gena (miš) Hrom. Hromosom 18 (miš) Bend 18|18 E1 Početak 65,712,983 bp Kraj 65,822,514 bp
Ontologija gena Molekularna funkcija • vezivanje sa DNK • vezivanje iona metala • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • jedro Biološki proces • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	55205	328977
Ensembl	ENSG00000074657	ENSMUSG00000042439
UniProt	Q9HCE3	Q6NXK2
RefSeq (mRNK)	NM_018181 NM_001318726 NM_001318727 NM_001318728 NM_001353525 NM_001353526 NM_001353527 NM_001353528 NM_001353529 NM_001353530 NM_001353531 NM_001353532 NM_001353533 NM_001353534 NM_001353535 NM_001353536 NM_001353537 NM_001353538 NM_001375912 NM_001375913	NM_207255 NM_001361051 NM_001361052 NM_001361053
RefSeq (bjelančevina)	NP_001305655 NP_001305656 NP_001305657 NP_060651 NP_001340454 NP_001340455 NP_001340456 NP_001340457 NP_001340458 NP_001340459 NP_001340460 NP_001340461 NP_001340462 NP_001340463 NP_001340464 NP_001340465 NP_001340466 NP_001340467 NP_001362841 NP_001362842	NP_997138 NP_001347980 NP_001347981 NP_001347982
Lokacija (UCSC)	Chr 18: 58.86 – 58.99 Mb	Chr 18: 65.71 – 65.82 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Dužina polipeptidnog lanca je 1.301 aminokiselina, sa molekulskom težinom od 141.696.

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10		20		30		40		50
MTMGDMKTPD		FDDLLAAFDI		PDMVDPKAAI		ESGHDDHESH		MKQNAHGEDD
SHAPSSSDVG		VSVIVKNVRN		IDSSEGGEKD		GHNPTGNGLH		NGFLTASSLD
SYSKDGAKSL		KGDVPASEVT		LKDSTFSQFS		PISSAEEFDD		DEKIEVDDPP
DKEDMRSSFR		SNVLTGSAPQ		QDYDKLKALG		GENSSKTGLS		TSGNVEKNKA
VKRETEASSI		NLSVYEPFKV		RKAEDKLKES		SDKVLENRVL		DGKLSSEKND
TSLPSVAPSK		TKSSSKLSSC		IAAIAALSAK		KAASDSCKEP		VANSRESSPL
PKEVNDSPRA		ADKSPESQNL		IDGTKKPSLK		QPDSPRSISS		ENSSKGSPSS
PAGSTPAIPK		VRIKTIKTSS		GEIKRTVTRV		LPEVDLDSGK		KPSEQTASVM
ASVTSLLSSP		ASAAVLSSPP		RAPLQSAVVT		NAVSPAELTP		KQVTIKPVAT
AFLPVSAVKT		AGSQVINLKL		ANNTTVKATV		ISAASVQSAS		SAIIKAANAI
QQQTVVVPAS		SLANAKLVPK		TVHLANLNLL		PQGAQATSEL		RQVLTKPQQQ
IKQAIINAAA		SQPPKKVSRV		QVVSSLQSSV		VEAFNKVLSS		VNPVPVYIPN
LSPPANAGIT		LPTRGYKCLE		CGDSFALEKS		LTQHYDRRSV		RIEVTCNHCT
KNLVFYNKCS		LLSHARGHKE		KGVVMQCSHL		ILKPVPADQM		IVSPSSNTST
STSTLQSPVG		AGTHTVTKIQ		SGITGTVISA		PSSTPITPAM		PLDEDPSKLC
RHSLKCLECN		EVFQDETSLA		THFQQAADTS		GQKTCTICQM		LLPNQCSYAS
HQRIHQHKSP		YTCPECGAIC		RSVHFQTHVT		KNCLHYTRRV		GFRCVHCNVV
YSDVAALKSH		IQGSHCEVFY		KCPICPMAFK		SAPSTHSHAY		TQHPGIKIGE
PKIIYKCSMC		DTVFTLQTLL		YRHFDQHIEN		QKVSVFKCPD		CSLLYAQKQL
MMDHIKSMHG		TLKSIEGPPN		LGINLPLSIK		PATQNSANQN		KEDTKSMNGK
EKLEKKSPSP		VKKSMETKKV		ASPGWTCWEC		DCLFMQRDVY		ISHVRKEHGK
QMKKHPCRQC		DKSFSSSHSL		CRHNRIKHKG		IRKVYACSHC		PDSRRTFTKR
LMLEKHVQLM		HGIKDPDLKE		MTDATNEEET		EIKEDTKVPS		PKRKLEEPVL
EFRPPRGAIT		QPLKKLKINV		FKVHKCAVCG		FTTENLLQFH		EHIPQHKSDG
SSYQCRECGL		CYTSHVSLSR		HLFIVHKLKE		PQPVSKQNGA		GEDNQQENKP
SHEDESPDGA		VSDRKCKVCA		KTFETEAALN		THMRTHGMAF		IKSKRMSSAE
K

Funkcija

Proteini cinkovog prsta vežu nukleinske kiseline i imaju važnu ulogu u različitim ćelijskim funkcijama, uključujući proliferacija ćelija, diferencijacija i apoptozu. Ovaj gen kodira protein cinkovog prsta i pripada porodici proteina cinka-prsta tipa Krüppel C2H2. Može biti uključen u proces transkripcije.