Protein cinkovog prsta 394 jest protein koji je kod ljudi kodiran genom ZNF394.[5]

ZNF394
Identifikatori
AliasiZNF394
Vanjski ID-jeviMGI: 1914485 HomoloGene: 11342 GeneCards: ZNF394
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za ZNF394
Genomska lokacija za ZNF394
Bend7q22.1Početak99,473,877 bp[1]
Kraj99,504,857 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za ZNF394
Genomska lokacija za ZNF394
Bend5|5 G2Početak145,131,756 bp[2]
Kraj145,138,678 bp[2]
Ontologija gena
Molekularna funkcija vezivanje sa DNK
GO:0001948, GO:0016582 vezivanje za proteine
nucleic acid binding
vezivanje iona metala
GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta intracellular anatomical structure
jedro
Biološki proces transcription, DNA-templated
GO:0009373 regulation of transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_032164
NM_001345967
NM_001345968

NM_023322

RefSeq (bjelančevina)

NP_001332896
NP_001332897
NP_115540

NP_075811

Lokacija (UCSC)Chr 7: 99.47 – 99.5 MbChr 5: 145.13 – 145.14 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 561 aminokiselina, а molekulska težina 64.256 Da.[6]

1020304050
MNSSLTAQRRGSDAELGPWVMAARSKDAAPSQRDGLLPVKVEEDSPGSWE
PNYPAASPDPETSRLHFRQLRYQEVAGPEEALSRLRELCRRWLRPELLSK
EQILELLVLEQFLTILPEELQAWVREHCPESGEEAVAVVRALQRALDGTS
SQGMVTFEDTAVSLTWEEWERLDPARRDFCRESAQKDSGSTVPPSLESRV
ENKELIPMQQILEEAEPQGQLQEAFQGKRPLFSKCGSTHEDRVEKQSGDP
LPLKLENSPEAEGLNSISDVNKNGSIEGEDSKNNELQNSARCSNLVLCQH
IPKAERPTDSEEHGNKCKQSFHMVTWHVLKPHKSDSGDSFHHSSLFETQR
QLHEERPYKCGNCGKSFKQRSDLFRHQRIHTGEKPYGCQECGKSFSQSAA
LTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHSRDKHFKCEECGET
CHISNLFRHQRLHKGERPYKCEECEKSFKQRSDLFKHHRIHTGEKPYGCS
VCGKRFNQSATLIKHQRIHTGEKPYKCLECGERFRQSTHLIRHQRIHQNK
VLSAGRGGSRL

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160908 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029627 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zinc finger protein 394". Pristupljeno 2. 3. 2016.
  6. ^ "UniProt, Q53GI3" (jezik: engleski). Pristupljeno 29. 9. 2021.

Dopunska literatura

uredi
  • Huang C, Wang Y, Li D, Li Y, Luo J, Yuan W, Ou Y, Zhu C, Zhang Y, Wang Z, Liu M, Wu X (2004). "Inhibition of transcriptional activities of AP-1 and c-Jun by a new zinc finger protein ZNF394". Biochem. Biophys. Res. Commun. 320 (4): 1298–305. doi:10.1016/j.bbrc.2004.06.080. PMID 15249231.