Protein 2 cinkovog prsta sa domenom MIZ jest protein koji je kod ljudi kodiran genom ZMIZ2.[5]

ZMIZ2
Identifikatori
AliasiZMIZ2
Vanjski ID-jeviOMIM: 611196 MGI: 106374 HomoloGene: 18000 GeneCards: ZMIZ2
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za ZMIZ2
Genomska lokacija za ZMIZ2
Bend7p13Početak44,748,581 bp[1]
Kraj44,769,881 bp[1]
Lokacija gena (miš)
Hromosom 11 (miš)
Hrom.Hromosom 11 (miš)[2]
Hromosom 11 (miš)
Genomska lokacija za ZMIZ2
Genomska lokacija za ZMIZ2
Bend11 A1|11 3.95 cMPočetak6,389,074 bp[2]
Kraj6,406,158 bp[2]
Obrazac RNK ekspresije




Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija vezivanje iona cinka
GO:0001948, GO:0016582 vezivanje za proteine
nuclear receptor coactivator activity
vezivanje iona metala
Ćelijska komponenta nuclear replication fork
mitohondrija
jedro
nukleoplazma
Biološki proces GO:0009373 regulation of transcription, DNA-templated
transcription, DNA-templated
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001300959
NM_031449
NM_174929

NM_001005867
NM_028601

RefSeq (bjelančevina)

NP_001287888
NP_113637
NP_777589

NP_001005867
NP_082877

Lokacija (UCSC)Chr 7: 44.75 – 44.77 MbChr 11: 6.39 – 6.41 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 520 aminokiselina, а molekulska težina 965.37 Da.[6]

1020304050
MNSMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAGSLSVVTTVWGVGN
ATQSQVLGNPMGPAGSPSGSSMMPGVAGGSSALTSPQCLGQQAFAEGGAN
KGYVQQGVYSRGGYPGAPGFTTGYAGGPGGLGLPSHAARPSTDFTQAAAA
AAVAAAAATATATATATVAALQEKQSQELSQYGAMGAGQSFNSQFLQHGG
PRGPSVPAGMNPTGIGGVMGPSGLSPLAMNPTRAAGMTPLYAGQRLPQHG
YPGPPQAQPLPRQGVKRTYSEVYPGQQYLQGGQYAPSTAQFAPSPGQPPA
PSPSYPGHRLPLQQGMTQSLSVPGPTGLHYKPTEQFNGQGASFNGGSVSY
SQPGLSGPTRSIPGYPSSPLPGNPTPPMTPSSSVPYMSPNQEVKSPFLPD
LKPNLNSLHSSPSGSGPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQ
LRDSVYKTLIMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIER
GDNKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVL
QGLLKKRLLPAEHCITKIKRNFSSGTIPGTPGPNGEDGVEQTAIKVSLKC
PITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEG
LEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVKPDMHIKEEPDGPAL
KRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSS
FLGPGTFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKSTAC
LPSQMAPAGHLDPTHNPGTPGLHTSNLGAPPGPQLHHSNPPPASRQSLGQ
ASLGPTGELAFSPATGVMGPPSMSGAGEAPEPALDLLPELTNPDELLSYL
GPPDLPTNNNDDLLSLFENN

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122515 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041164 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZMIZ2 zinc finger, MIZ-type containing 2".
  6. ^ "UniProt, Q8NF64" (jezik: engleski). Pristupljeno 29. 9. 2021.

Dopunska literatura

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