Protein 1 cinkovog prsta sa domenima KRAB i SCAN jest protein koji je kod ljudi kodiran genom ZKSCAN1.[5]

ZKSCAN1
Identifikatori
AliasiZKSCAN1
Vanjski ID-jeviOMIM: 601260 MGI: 1921820 HomoloGene: 34523 GeneCards: ZKSCAN1
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za ZKSCAN1
Genomska lokacija za ZKSCAN1
Bend7q22.1Početak100,015,572 bp[1]
Kraj100,041,689 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za ZKSCAN1
Genomska lokacija za ZKSCAN1
Bend5|5 G2Početak138,083,346 bp[2]
Kraj138,106,084 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
nucleic acid binding
vezivanje iona metala
vezivanje sa DNK
GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta intracellular anatomical structure
jedro
Biološki proces GO:0009373 regulation of transcription, DNA-templated
transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_001287054
NM_001287055
NM_003439
NM_001346579
NM_001346580

NM_001346581

NM_029869
NM_133906

RefSeq (bjelančevina)
NP_001273983
NP_001273984
NP_001333508
NP_001333509
NP_001333510

NP_003430

NP_084145
NP_598667

Lokacija (UCSC)Chr 7: 100.02 – 100.04 MbChr 5: 138.08 – 138.11 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 563 aminokiseline, а molekulska težina 63.630 Da.[6]

1020304050
MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPP
DPEIFRQRFRRFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLV
LEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGP
EMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRKPRLLQSRALPAAHI
PAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNLARRN
LSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKE
FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREK
GKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHT
GEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLIL
HQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNR
NSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPA
SLDAFGAFLKSCV

Također pogledajte

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Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106261 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029729 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZKSCAN1 zinc finger with KRAB and SCAN domains 1".
  6. ^ "UniProt, P17029" (jezik: engleski). Pristupljeno 30. 9. 2021.

Dopunska literatura

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