USP52

USP52
Identifikatori
Aliasi	PAN2
Vanjski ID-jevi	OMIM: 617447 MGI: 1918984 HomoloGene: 5918 GeneCards: PAN2
Lokacija gena (čovjek)
Hrom.	Hromosom 12 (čovjek)
Kraj	56,334,053 bp
Lokacija gena (miš)
Hrom.	Hromosom 10 (miš)
Kraj	128,157,227 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• poly(A)-specific ribonuclease activity; • nuclease activity; • exonuclease activity; • 3'-5'-exoribonuclease activity; • GO:0001948, GO:0016582 vezivanje za proteine; • hydrolase activity; • nucleic acid binding; • vezivanje iona metala;
Ćelijska komponenta	• citoplazma; • PAN complex; • citosol; • P-tijelo; • jedro;
Biološki proces	• nuclear-transcribed mRNA poly(A) tail shortening; • mRNA processing; • nucleic acid phosphodiester bond hydrolysis; • RNA phosphodiester bond hydrolysis, exonucleolytic; • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; • positive regulation of cytoplasmic mRNA processing body assembly;
	Izvori:Amigo / QuickGO
Ortolozi
	9924
	103135
	ENSG00000135473
	ENSMUSG00000005682
	Q504Q3
	Q8BGF7
	NM_014871; NM_001127460; NM_001166279
	NM_001252326; NM_001252327; NM_133992; NM_001358822
	NP_001120932; NP_001159751; NP_055686
	NP_001239255; NP_001239256; NP_598753; NP_001345751
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Podjedinica 2 PAB-ovisne poli(A)-specifične ribonukleaze je enzim koji je kod ljudi kodiran genom PAN2.^[5]^[6]^[7]

Aminokiselinska sekvenca

Simboli

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135473 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000005682 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Puente XS, Sánchez LM, Overall CM, López-Otín C (juli 2003). "Human and mouse proteases: a comparative genomic approach". Nature Reviews. Genetics. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
^ Uchida N, Hoshino S, Katada T (januar 2004). "Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein". The Journal of Biological Chemistry. 279 (2): 1383–91. doi:10.1074/jbc.M309125200. PMID 14583602.
^ "Entrez Gene: USP52 ubiquitin specific peptidase 52".
^ "UniProt, Q504Q3". Pristupljeno 14. 8. 2021.

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