TOE1
Ciljni EGR1 protein 1 jest protein koji je kod ljudi kodiran genom TOE1 sa hromosoma 1.[5][6]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 510 aminokiselina, a molekulska težina 56.548 Da.[7]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MAADSDDGAV | SAPAASDGGV | SKSTTSGEEL | VVQVPVVDVQ | SNNFKEMWPS | ||||
LLLAIKTANF | VAVDTELSGL | GDRKSLLNQC | IEERYKAVCH | AARTRSILSL | ||||
GLACFKRQPD | KGEHSYLAQV | FNLTLLCMEE | YVIEPKSVQF | LIQHGFNFNQ | ||||
QYAQGIPYHK | GNDKGDESQS | QSVRTLFLEL | IRARRPLVLH | NGLIDLVFLY | ||||
QNFYAHLPES | LGTFTADLCE | MFPAGIYDTK | YAAEFHARFV | ASYLEYAFRK | ||||
CERENGKQRA | AGSPHLTLEF | CNYPSSMRDH | IDYRCCLPPA | THRPHPTSIC | ||||
DNFSAYGWCP | LGPQCPQSHD | IDLIIDTDEA | AAEDKRRRRR | RREKRKRALL | ||||
NLPGTQTSGE | AKDGPPKKQV | CGDSIKPEET | EQEVAADETR | NLPHSKQGNK | ||||
NDLEMGIKAA | RPEIADRATS | EVPGSQASPN | PVPGDGLHRA | GFDAFMTGYV | ||||
MAYVEVSQGP | QPCSSGPWLP | ECHNKVYLSG | KAVPLTVAKS | QFSRSSKAHN | ||||
QKMKLTWGSS |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000132773 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028688 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ De Belle I, Wu JX, Sperandio S, Mercola D, Adamson ED (Apr 2003). "In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1". J Biol Chem. 278 (16): 14306–12. doi:10.1074/jbc.M210502200. PMID 12562764.
- ^ "Entrez Gene: TOE1 target of EGR1, member 1 (nuclear)".
- ^ "UniProt, Q96GM8" (jezik: eng.). Pristupljeno 3. 12. 2021.CS1 održavanje: nepoznati jezik (link)
Dopunska literatura
uredi- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Will CL, Schneider C, Hossbach M, et al. (2004). "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA. 10 (6): 929–41. doi:10.1261/rna.7320604. PMC 1370585. PMID 15146077.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1995). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening". Genomics. 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID 7829101.