Protein 7 sa THAP domenom jest protein koji je kod ljudi kodiran genom THAP7 sa hromosoma 22.[5][6]

THAP7
Identifikatori
AliasiTHAP7
Vanjski ID-jeviOMIM: 609518 MGI: 1916259 HomoloGene: 12293 GeneCards: THAP7
Lokacija gena (čovjek)
Hromosom 22 (čovjek)
Hrom.Hromosom 22 (čovjek)[1]
Hromosom 22 (čovjek)
Genomska lokacija za THAP7
Genomska lokacija za THAP7
Bend22q11.21Početak20,999,104 bp[1]
Kraj21,002,196 bp[1]
Lokacija gena (miš)
Hromosom 16 (miš)
Hrom.Hromosom 16 (miš)[2]
Hromosom 16 (miš)
Genomska lokacija za THAP7
Genomska lokacija za THAP7
Bend16 A3|16Početak17,345,846 bp[2]
Kraj17,349,000 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija vezivanje sa DNK
C2H2 zinc finger domain binding
GO:0001948, GO:0016582 vezivanje za proteine
vezivanje iona metala
protein N-terminus binding
nucleic acid binding
vezivanje identičnih proteina
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta nuclear speck
hromosom
jedro
Jedarna membrana
intracellular membrane-bounded organelle
Biološki proces GO:0045996 negative regulation of transcription, DNA-templated
GO:0009373 regulation of transcription, DNA-templated
transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_030573
NM_001008695
NM_001008696

NM_026909

RefSeq (bjelančevina)

NP_001008695
NP_085050

NP_081185

Lokacija (UCSC)Chr 22: 21 – 21 MbChr 16: 17.35 – 17.35 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 309 aminokiselina, a molekulska težina 34.414 Da.[6]

1020304050
MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSG
QGLWDPASEYIYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLR
RTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPV
EEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQ
PSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALDA
LDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF
AMQLSSSMA

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000184436 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022760 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.
  6. ^ a b "Entrez Gene: THAP7 THAP domain containing 7".

Dopunska literatura

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