THAP7
Protein 7 sa THAP domenom jest protein koji je kod ljudi kodiran genom THAP7 sa hromosoma 22.[5][6]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 309 aminokiselina, a molekulska težina 34.414 Da.[6]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MPRHCSAAGC | CTRDTRETRN | RGISFHRLPK | KDNPRRGLWL | ANCQRLDPSG | ||||
QGLWDPASEY | IYFCSKHFEE | DCFELVGISG | YHRLKEGAVP | TIFESFSKLR | ||||
RTTKTKGHSY | PPGPAEVSRL | RRCRKRCSEG | RGPTTPFSPP | PPADVTCFPV | ||||
EEASAPATLP | ASPAGRLEPG | LSSPFSDLLG | PLGAQADEAG | CSAQPSPERQ | ||||
PSPLEPRPVS | PSAYMLRLPP | PAGAYIQNEH | SYQVGSALLW | KRRAEAALDA | ||||
LDKAQRQLQA | CKRREQRLRL | RLTKLQQERA | REKRAQADAR | QTLKEHVQDF | ||||
AMQLSSSMA |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000184436 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022760 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.
- ^ a b "Entrez Gene: THAP7 THAP domain containing 7".
Dopunska literatura
uredi- Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
- Macfarlan T, Parker JB, Nagata K, Chakravarti D (2006). "Thanatos-associated protein 7 associates with template activating factor-Ibeta and inhibits histone acetylation to repress transcription". Mol. Endocrinol. 20 (2): 335–47. doi:10.1210/me.2005-0248. PMID 16195249.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Macfarlan T, Kutney S, Altman B, et al. (2005). "Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor". J. Biol. Chem. 280 (8): 7346–58. doi:10.1074/jbc.M411675200. PMID 15561719.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.