Protein 6 sa THAP-domenom jest protein koji je kod ljudi kodiran genom THAP6 sa hromosoma 4 .[ 3] [ 4]
THAP6 Identifikatori Aliasi THAP6 Vanjski ID-jevi OMIM : 612535 HomoloGene : 16985 GeneCards : THAP6 Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • vezivanje iona metala • vezivanje sa DNK • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • microtubule cytoskeleton Biološki proces • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi Vrste Čovjek Miš Entrez Ensembl UniProt RefSeq (mRNK) RefSeq (bjelančevina) Lokacija (UCSC) Chr 4: 75.51 – 75.55 Mb n/a PubMed pretraga[ 2] n/a Wikipodaci
Aminokiselinska sekvenca
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Dužina polipeptidnog lanca je 222 aminokiseline , а molekulska težina 25.691 Da .[ 5]
10 20 30 40 50 MVKCCSAIGC ASRCLPNSKL KGLTFHVFPT DENIKRKWVL AMKRLDVNAA GIWEPKKGDV LCSRHFKKTD FDRSAPNIKL KPGVIPSIFD SPYHLQGKRE KLHCRKNFTL KTVPATNYNH HLVGASSCIE EFQSQFIFEH SYSVMDSPKK LKHKLDHVIG ELEDTKESLR NVLDREKRFQ KSLRKTIREL KDECLISQET ANRLDTFCWD CCQESIEQDY IS
^ a b c GRCh38: Ensembl release 89: ENSG00000174796 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci . 28 (2): 66–9. doi :10.1016/S0968-0004(02)00013-0 . PMID 12575992 . ^ "Entrez Gene: THAP6 THAP domain containing 6" .^ "UniProt, Q8TBB0" (jezik: engleski). Pristupljeno 29. 10. 2021 .
Dopunska literatura
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Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination" . Genome Res . 10 (11): 1788–95. doi :10.1101/gr.143000 . PMC 310948 PMID 11076863 . Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" . EMBO Rep . 1 (3): 287–92. doi :10.1093/embo-reports/kvd058 . PMC 1083732 PMID 11256614 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline" . Genome Res . 14 (10B): 2136–44. doi :10.1101/gr.2576704 . PMC 528930 PMID 15489336 . Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65. doi :10.1101/gr.4039406 . PMC 1356129 PMID 16344560 . Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006" . Nucleic Acids Res . 34 (Database issue): D415–8. doi :10.1093/nar/gkj139 . PMC 1347501 PMID 16381901 . 
