Kornifin-B jest protein koji je kod ljudi kodiran genom SPRR1B sa hromosoma 1.[3][4][5]

SPRR1B
Identifikatori
AliasiSPRR1B
Vanjski ID-jeviOMIM: 182266 HomoloGene: 105655 GeneCards: SPRR1B
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za SPRR1B
Genomska lokacija za SPRR1B
Bend1q21.3Početak153,031,203 bp[1]
Kraj153,032,900 bp[1]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija protein-macromolecule adaptor activity
structural molecule activity
Ćelijska komponenta cornified envelope
citosol
citoplazma
Biološki proces keratinization
keratinocyte differentiation
epidermis development
GO:0051357, GO:0051358, GO:0051359 peptide cross-linking
cornification
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_003125

n/a

RefSeq (bjelančevina)

NP_003116

n/a

Lokacija (UCSC)Chr 1: 153.03 – 153.03 Mbn/a
PubMed pretraga[2]n/a
Wikipodaci
Pogledaj/uredi – čovjek

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 89 aminokiselina, a molekulska težina 9.888 Da.[6]

1020304050
MSSQQQKQPCTPPPQLQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCH
PKVPEPCQPKVPEPCHPKVPEPCPSIVTPAPAQQKTKQK

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000169469 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (Aug 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins". Genomics. 16 (3): 630–7. doi:10.1006/geno.1993.1240. PMID 8325635.
  4. ^ Marvin KW, George MD, Fujimoto W, Saunders NA, Bernacki SH, Jetten AM (Dec 1992). "Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids". Proc Natl Acad Sci U S A. 89 (22): 11026–30. Bibcode:1992PNAS...8911026M. doi:10.1073/pnas.89.22.11026. PMC 50476. PMID 1438308.
  5. ^ "Entrez Gene: SPRR1B small proline-rich protein 1B (cornifin)".
  6. ^ "UniProt, P22528" (jezik: engleski). Pristupljeno 19. 12. 2021.

Dopunska literatura

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