Mitohondrijska seril-tRNK sintetaza je enzim koji je kod ljudi kodiran genom SARS2.[5][6]

SARS2
Identifikatori
AliasiSARS2
Vanjski ID-jeviOMIM: 612804 MGI: 1919234 HomoloGene: 6073 GeneCards: SARS2
Lokacija gena (čovjek)
Hromosom 19 (čovjek)
Hrom.Hromosom 19 (čovjek)[1]
Hromosom 19 (čovjek)
Genomska lokacija za SARS2
Genomska lokacija za SARS2
Bend19q13.2Početak38,915,266 bp[1]
Kraj38,930,763 bp[1]
Lokacija gena (miš)
Hromosom 7 (miš)
Hrom.Hromosom 7 (miš)[2]
Hromosom 7 (miš)
Genomska lokacija za SARS2
Genomska lokacija za SARS2
Bend7 B1|7 16.91 cMPočetak28,441,417 bp[2]
Kraj28,453,296 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija aminoacyl-tRNA ligase activity
nucleotide binding
ligase activity
ATP binding
serine-tRNA ligase activity
vezivanje sa RNK
Ćelijska komponenta citoplazma
mitochondrial matrix
mitohondrija
Biološki proces tRNA aminoacylation for protein translation
Biosinteza bjelančevina
seryl-tRNA aminoacylation
selenocysteinyl-tRNA(Sec) biosynthetic process
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_017827
NM_001145901

NM_023637

RefSeq (bjelančevina)

NP_001139373
NP_060297

NP_076126

Lokacija (UCSC)Chr 19: 38.92 – 38.93 MbChr 7: 28.44 – 28.45 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš


Aminokiselinska sekvence

Simboli
1020304050
MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYARE
GYSALPQLDIERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQ
EQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELV
HLYPREAQLEEQFYLQALKLPNQTHPDVPVGDESQARVLHMVGDKPVFSF
QPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKL
LRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTA
EVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTK
VEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPA
YRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTV
NATACAVPRLLIALLESNQQKDGSVLVPPALQSYLGTDRITAPTHVPLQY
IGPNQPRKPGLPGQPAVS

Reference

uredi
  1. ^ a b c ENSG00000283104 GRCh38: Ensembl release 89: ENSG00000104835, ENSG00000283104 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070699 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yokogawa T, Shimada N, Takeuchi N, Benkowski L, Suzuki T, Omori A, Ueda T, Nishikawa K, Spremulli LL, Watanabe K (Aug 2000). "Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase". J Biol Chem. 275 (26): 19913–20. doi:10.1074/jbc.M908473199. PMID 10764807.
  6. ^ "Entrez Gene: SARS2 seryl-tRNA synthetase 2, mitochondrial".

Dopunska kiteratura

uredi