SAP ribonukleoprotein sa domenom je protein koji je kod ljudi kodiran genom SARNP.[4][5][6]

SARNP
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

2DO1

Identifikatori
AliasiSARNP
Vanjski ID-jeviOMIM: 610049 MGI: 1913368 HomoloGene: 41628 GeneCards: SARNP
Lokacija gena (miš)
Hromosom 10 (miš)
Hrom.Hromosom 10 (miš)[1]
Hromosom 10 (miš)
Genomska lokacija za SARNP
Genomska lokacija za SARNP
Bend10|10 D3Početak128,817,333 bp[1]
Kraj128,877,629 bp[1]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija vezivanje sa DNK
GO:0001948, GO:0016582 vezivanje za proteine
vezivanje sa RNK
GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific
protein C-terminus binding
RS domain binding
Ćelijska komponenta nuclear speck
transcription export complex
jedro
nukleoplazma
cytoplasmic ribonucleoprotein granule
Biološki proces mRNA transport
GO:0009373 regulation of transcription, DNA-templated
regulation of translation
transcription, DNA-templated
RNA export from nucleus
mRNA export from nucleus
termination of RNA polymerase II transcription
mRNA 3'-end processing
GO:0015915 transport
GO:1901227 negative regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_033082

NM_025364

RefSeq (bjelančevina)

NP_149073

NP_079640
NP_001346332
NP_001346333
NP_001346334
NP_001346335

NP_001346336

Lokacija (UCSC)n/aChr 10: 128.82 – 128.88 Mb
PubMed pretraga[2][3]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 210 aminokiselina, a molekulska težina 23.671 Da.[7].

Simboli
1020304050
MATETVELHKLKLAELKQECLARGLETKGIKQDLIHRLQAYLEEHAEEEA
NEEDVLGDETEEEETKPIELPVKEEEPPEKTVDVAAEKKVVKITSEIPQT
ERMQKRAERFNVPVSLESKKAARAARFGISSVPTKGLSSDNKPMVNLDKL
KERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKK
RKRAERFGIA

Reference

uredi
  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000078427 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Choong ML, Tan LK, Lo SL, Ren EC, Ou K, Ong SE, Liang RC, Seow TK, Chung MC (maj 2001). "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors". FEBS Lett. 496 (2–3): 109–16. doi:10.1016/S0014-5793(01)02409-7. PMID 11356193. S2CID 24122700.
  5. ^ Fukuda S, Wu DW, Stark K, Pelus LM (Mar 2002). "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29". Biochem Biophys Res Commun. 292 (3): 593–600. doi:10.1006/bbrc.2002.6680. PMID 11922608.
  6. ^ "Entrez Gene: CIP29 cytokine induced protein 29 kDa".
  7. ^ "UniProt, P82979". Pristupljeno 14. 8. 2021.

Dopunska literatura

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Vanjski linkovi

uredi