RPL36A

Podjedinica 60S ribosomskog proteina L36a je protein koji je kod ljudi kodiran genom RPL36A.

RPL36A
Dostupne strukture PDB Pretraga Human UniProta: PDBe RCSB Spisak PDB ID kodova 4UG0, 4V6X, 5AJ0, 3J7R, 4V5Z, 4UJD, 3J7P, 4D67, 3J92, 4D5Y, 3J7Q, 4UJE, 3J7O, 4UJC
Identifikatori
Aliasi	RPL36A
Vanjski ID-jevi	OMIM: 300902 HomoloGene: 776 GeneCards: RPL36A
Lokacija gena (čovjek) Hrom. Hromosom X Bend Xq22.1 Početak 101,390,824 bp Kraj 101,396,155 bp
Ontologija gena Molekularna funkcija • structural constituent of ribosome • GO:0001948, GO:0016582 vezivanje za proteine • vezivanje sa RNK Ćelijska komponenta • citoplazma • ribozom • intracellular anatomical structure • cytosolic large ribosomal subunit • citosol • ćelijska membrana • Endoplazmatski retikulum • polysomal ribosome Biološki proces • cytoplasmic translation • viral transcription • SRP-dependent cotranslational protein targeting to membrane • translational initiation • Nonsens-posredovano propadanje iRNK • Biosinteza bjelančevina • rRNA processing Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	6173	n/a
Ensembl	ENSG00000241343	n/a
UniProt	P83881	n/a
RefSeq (mRNK)	NM_021029 NM_001199972	n/a
RefSeq (bjelančevina)	NP_066357	n/a
Lokacija (UCSC)	Chr X: 101.39 – 101.4 Mb	n/a
PubMed pretraga		n/a
Wikipodaci
Pogledaj/uredi – čovjek

Citoplazmatski ribosomi , organele koje kataliziraju sintezu proteina, sastoje se od male 40S i velike 60S podjedinice. Ove podjedinice zajedno se sastoje od četiri tipa RNK i približno 80 strukturno različitih proteina. Ovaj gen kodira ribosomani protein koji je komponenta podjedinice 60S. Protein, koji ima sličnu sekvencu sa ribosomnim proteinom kvasca L44, pripada porodici ribosomnih proteina L44E (L36AE). Iako se ovaj gen naziva ribosomni protein L44 (RPL44), njegov službeni naziv je ribosomni protein L36a (RPL36A). Ovaj gen i ljudski gen zvanično zvani ribosomni protein sličan L36a (RPL36AL) kodiraju gotovo identične proteine; međutim, oni su različiti geni. Kao što je tipskoo za gene koji kodiraju ribosomske proteine, postoji više obrađenih pseudogena ovog gena raspršenih širom genoma.

Aminokiaelinska sekvenca

Dužina polipeptidnog lanca je 106 aminokiselina, а molekulska težina 12.441 Da.

10		20		30		40		50
MVNVPKTRRT		FCKKCGKHQP		HKVTQYKKGK		DSLYAQGKRR		YDRKQSGYGG
QTKPIFRKKA		KTTKKIVLRL		ECVEPNCRSK		RMLAIKRCKH		FELGGDKKRK
GQVIQF

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

• Y: Tirozin

Dopunska literatura

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