REXO4
RNK-egzonukleaza 4 je enzim koji je kod ljudi kodiran genom REXO4.[5][6]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 422 aminokiseline, а molekulska težina 46.672 Da.[7]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MGKAKVPASK | RAPSSPVAKP | GPVKTLTRKK | NKKKKRFWKS | KAREVSKKPA | ||||
SGPGAVVRPP | KAPEDFSQNW | KALQEWLLKQ | KSQAPEKPLV | ISQMGSKKKP | ||||
KIIQQNKKET | SPQVKGEEMP | AGKDQEASRG | SVPSGSKMDR | RAPVPRTKAS | ||||
GTEHNKKGTK | ERTNGDIVPE | RGDIEHKKRK | AKEAAPAPPT | EEDIWFDDVD | ||||
PADIEAAIGP | EAAKIARKQL | GQSEGSVSLS | LVKEQAFGGL | TRALALDCEM | ||||
VGVGPKGEES | MAARVSIVNQ | YGKCVYDKYV | KPTEPVTDYR | TAVSGIRPEN | ||||
LKQGEELEVV | QKEVAEMLKG | RILVGHALHN | DLKVLFLDHP | KKKIRDTQKY | ||||
KPFKSQVKSG | RPSLRLLSEK | ILGLQVQQAE | HCSIQDAQAA | MRLYVMVKKE | ||||
WESMARDRRP | LLTAPDHCSD | DA |
Reference
uredi- ^ a b c ENSG00000148300 GRCh38: Ensembl release 89: ENSG00000280706, ENSG00000148300 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052406 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Kwiatkowska J, Slomski R, Jozwiak S, Short MP, Kwiatkowski DJ (Nov 1997). "Human XPMC2H: cDNA cloning, mapping to 9q34, genomic structure, and evaluation as TSC1". Genomics. 44 (3): 350–4. doi:10.1006/geno.1997.4874. PMID 9325058.
- ^ "Entrez Gene: REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)".
- ^ "UniProt, Q9GZR2". Pristupljeno 11. 9. 2021.
Dopunska literatura
uredi- Montano MM, Wittmann BM, Bianco NR (2000). "Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity". J. Biol. Chem. 275 (44): 34306–13. doi:10.1074/jbc.M003880200. PMID 10908561.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.