POLR1B

Podjedinica RPA2 DNK-usmjerene RNK-polimeraze polimeraze I jest enzim koji je kod ljudi kodiran genom POLR1B sa hromosoma 2.

POLR1B
Identifikatori
Aliasi	POLR1B
Vanjski ID-jevi	OMIM: 602000 MGI: 108014 HomoloGene: 7133 GeneCards: POLR1B
Lokacija gena (čovjek) Hrom. Hromosom 2 (čovjek) Bend 2q14.1 Početak 112,541,915 bp Kraj 112,579,818 bp
Lokacija gena (miš) Hrom. Hromosom 2 (miš) Bend 2|2 F1 Početak 128,942,915 bp Kraj 128,968,514 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • aktivnost sa transferazom • vezivanje sa DNK • nucleotidyltransferase activity • ribonucleoside binding • vezivanje iona metala • DNA-directed 5'-3' RNA polymerase activity • GO:0001948, GO:0016582 vezivanje za proteine • RNA polymerase I activity Ćelijska komponenta • nukleoplazma • Jedarce • RNA polymerase I complex • jedro • citosol Biološki proces • termination of RNA polymerase I transcription • epigenetic maintenance of chromatin in transcription-competent conformation • transcription initiation from RNA polymerase I promoter • rRNA transcription • transcription, DNA-templated • embryo implantation • nucleologenesis • GO:0001183 transcription elongation from RNA polymerase I promoter Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	84172	20017
Ensembl	ENSG00000125630	ENSMUSG00000027395
UniProt	Q9H9Y6	P70700
RefSeq (mRNK)	NM_019014 NM_001137604 NM_001282772 NM_001282774 NM_001282776 NM_001282777 NM_001282779 NM_001371969 NM_001371970 NM_001371971	NM_009086
RefSeq (bjelančevina)	NP_001131076 NP_001269701 NP_001269703 NP_001269705 NP_001269706 NP_001269708 NP_061887 NP_001358898 NP_001358899 NP_001358900	NP_033112
Lokacija (UCSC)	Chr 2: 112.54 – 112.58 Mb	Chr 2: 128.94 – 128.97 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Amiokiselininska sekvenca

Dužina polipeptidnog lanca je 1.135 aminokiselina, a molekulska težina 128.229 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MDPGSRWRNL		PSGPSLKHLT		DPSYGIPREQ		QKAALQELTR		AHVESFNYAV
HEGLGLAVQA		IPPFEFAFKD		ERISFTILDA		VISPPTVPKG		TICKEANVYP
AECRGRRSTY		RGKLTADINW		AVNGISKGII		KQFLGYVPIM		VKSKLCNLRN
LPPQALIEHH		EEAEEMGGYF		IINGIEKVIR		MLIMPRRNFP		IAMIRPKWKT
RGPGYTQYGV		SMHCVREEHS		AVNMNLHYLE		NGTVMLNFIY		RKELFFLPLG
FALKALVSFS		DYQIFQELIK		GKEDDSFLRN		SVSQMLRIVM		EEGCSTQKQV
LNYLGECFRV		KLNVPDWYPN		EQAAEFLFNQ		CICIHLKSNT		EKFYMLCLMT
RKLFALAKGE		CMEDNPDSLV		NQEVLTPGQL		FLMFLKEKLE		GWLVSIKIAF
DKKAQKTSVS		MNTDNLMRIF		TMGIDLTKPF		EYLFATGNLR		SKTGLGLLQD
SGLCVVADKL		NFIRYLSHFR		CVHRGADFAK		MRTTTVRRLL		PESWGFLCPV
HTPDGEPCGL		MNHLTAVCEV		VTQFVYTASI		PALLCNLGVT		PIDGAPHRSY
SECYPVLLDG		VMVGWVDKDL		APGIADSLRH		FKVLREKRIP		PWMEVVLIPM
TGKPSLYPGL		FLFTTPCRLV		RPVQNLALGK		EELIGTMEQI		FMNVAIFEDE
VFAGVTTHQE		LFPHSLLSVI		ANFIPFSDHN		QSPRNMYQCQ		MGKQTMGFPL
LTYQDRSDNK		LYRLQTPQSP		LVRPSMYDYY		DMDNYPIGTN		AIVAVISYTG
YDMEDAMIVN		KASWERGFAH		GSVYKSEFID		LSEKIKQGDS		SLVFGIKPGD
PRVLQKLDDD		GLPFIGAKLQ		YGDPYYSYLN		LNTGESFVMY		YKSKENCVVD
NIKVCSNDTG		SGKFKCVCIT		MRVPRNPTIG		DKFASRHGQK		GILSRLWPAE
DMPFTESGMV		PDILFNPHGF		PSRMTIGMLI		ESMAGKSAAL		HGLCHDATPF
IFSEENSALE		YFGEMLKAAG		YNFYGTERLY		SGISGLELEA		DIFIGVVYYQ
RLRHMVSDKF		QVRTTGARDR		VTNQPIGGRN		VQGGIRFGEM		ERDALLAHGT
SFLLHDRLFN		CSDRSVAHVC		VKCGSLLSPL		LEKPPPSWSA		MRNRKYNCTL
CSRSDTIDTV		SVPYVFRYFV		AELAAMNIKV		KLDVV

Dopunska literatura

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