Jedarni receptor-vezujući faktor 2 je protein koji je kod ljudi kodiran genom NRBF2.[5][6]

NRBF2
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

4ZEY

Identifikatori
AliasiNRBF2
Vanjski ID-jeviOMIM: 616477 MGI: 1354950 HomoloGene: 41473 GeneCards: NRBF2
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za NRBF2
Genomska lokacija za NRBF2
Bend10q21.3Početak63,133,247 bp[1]
Kraj63,155,031 bp[1]
Lokacija gena (miš)
Hromosom 10 (miš)
Hrom.Hromosom 10 (miš)[2]
Hromosom 10 (miš)
Genomska lokacija za NRBF2
Genomska lokacija za NRBF2
Bend10|10 B5.1Početak67,102,468 bp[2]
Kraj67,121,084 bp[2]
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta citoplazma
phosphatidylinositol 3-kinase complex, class III
Autofagosom
jedro
nukleoplazma
GO:0016023 citoplazmatska vezikula
Biološki proces transcription initiation from RNA polymerase II promoter
GO:0009373 regulation of transcription, DNA-templated
response to endoplasmic reticulum stress
transcription, DNA-templated
regulation of lipid kinase activity
Autofagija
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001282405
NM_030759

NM_001036293

RefSeq (bjelančevina)

NP_001269334
NP_110386

NP_001031370
NP_001388976
NP_001388977

Lokacija (UCSC)Chr 10: 63.13 – 63.16 MbChr 10: 67.1 – 67.12 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 287 aminokiselina, a molekulska težina 32.378 Da.[7]

1020304050
MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMKLTQS
EQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQT
SHKPSAEDAEGQSPLSQKYSPSTEKCLPEIQGIFDRDPDTLLYLLQQKSE
PAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLK
AEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANT
GKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000148572 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075000 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yasumo H, Masuda N, Furusawa T, Tsukamoto T, Sadano H, Osumi T (maj 2000). "Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors". Biochim Biophys Acta. 1490 (1–2): 189–97. doi:10.1016/S0167-4781(99)00244-4. PMID 10786636.
  6. ^ "Entrez Gene: NRBF2 nuclear receptor binding factor 2".
  7. ^ "UniProt, Q96F24". Pristupljeno 3. 9. 2021.

Dopunska literatura

uredi

Vanjski linkovi

uredi