NOL9

NOL9
Identifikatori
Aliasi	NOL9
Vanjski ID-jevi	MGI: 1921285 HomoloGene: 32589 GeneCards: NOL9
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	6,554,513 bp
Lokacija gena (miš)
Hrom.	Hromosom 4 (miš)
Kraj	152,145,951 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• aktivnost sa transferazom; • nucleotide binding; • polynucleotide 5'-hydroxyl-kinase activity; • GO:0001948, GO:0016582 vezivanje za proteine; • ATP binding; • vezivanje sa RNK; • kinase activity;
Ćelijska komponenta	• membrana; • jedro; • nukleoplazma; • Jedarce; • intermediate filament cytoskeleton;
Biološki proces	• cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • maturation of 5.8S rRNA; • Fosforilacija; • rRNA processing;
	Izvori:Amigo / QuickGO
Ortolozi
	79707
	74035
	ENSG00000162408
	ENSMUSG00000028948
	Q5SY16
	Q3TZX8
	NM_024654
	NM_001159599; NM_028727; NM_001378856
	NP_078930
	NP_001153071; NP_083003; NP_001365785
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Jedarcetov protein 9 jest protein koji je kod ljudi kodiran genom NOL9 sa hromosoma 1.^[5]^[6]

Aminokiselinska sekvenca uredi

Dužina polipeptidnog lanca je 702 aminokiseline, a molekulska težina 79.323 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MADSGLLLKR	GSCRSTWLRV	RKARPQLILS	RRPRRRLGSL	RWCGRRRLRW
RLLQAQASGV	DWREGARQVS	RAAAARRPNT	ATPSPIPSPT	PASEPESEPE
LESASSCHRP	LLIPPVRPVG	PGRALLLLPV	EQGFTFSGIC	RVTCLYGQVQ
VFGFTISQGQ	PAQDIFSVYT	HSCLSIHALH	YSQPEKSKKE	LKREARNLLK
SHLNLDDRRW	SMQNFSPQCS	IVLLEHLKTA	TVNFITSYPG	SSYIFVQESP
TPQIKPEYLA	LRSVGIRREK	KRKGLQLTES	TLSALEELVN	VSCEEVDGCP
VILVCGSQDV	GKSTFNRYLI	NHLLNSLPCV	DYLECDLGQT	EFTPPGCISL
LNITEPVLGP	PFTHLRTPQK	MVYYGKPSCK	NNYENYIDIV	KYVFSAYKRE
SPLIVNTMGW	VSDQGLLLLI	DLIRLLSPSH	VVQFRSDHSK	YMPDLTPQYV
DDMDGLYTKS	KTKMRNRRFR	LAAFADALEF	ADEEKESPVE	FTGHKLIGVY
TDFAFRITPR	NRESHNKILR	DLSILSYLSQ	LQPPMPKPLS	PLHSLTPYQV
PFNAVALRIT	HSDVAPTHIL	YAVNASWVGL	CKIQDDVRGY	TNGPILLAQT
PICDCLGFGI	CRGIDMEKRL	YHILTPVPPE	ELRTVNCLLV	GAIAIPHCVL
KCQRGIEGTV	PYVTTDYNFK	LPGASEKIGA	REPEEAHKEK	PYRRPKFCRK
MK

Reference uredi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162408 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028948 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
^ "Entrez Gene: NOL9 nucleolar protein 9".
^ "UniProt, Q5SY16" (jezik: eng.). Pristupljeno 3. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura uredi

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Mol. Vis. 8: 205–20. PMID 12107410.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162408 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028948 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: NOL9 nucleolar protein 9".

[UniProt-7] "UniProt, Q5SY16" (jezik: eng.). Pristupljeno 3. 12. 2021.CS1 održavanje: nepoznati jezik (link)

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