NOC2L

Homolog jedarcetovog kompleksa proteina 2 jest protein koji je kod ljudi kodiran genom NOC2L sa hromosoma 1.

NOC2L
Identifikatori
Aliasi	NOC2L
Vanjski ID-jevi	OMIM: 610770 MGI: 1931051 HomoloGene: 6980 GeneCards: NOC2L
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek) Bend 1p36.33 Početak 944,203 bp Kraj 959,309 bp
Lokacija gena (miš) Hrom. Hromosom 4 (miš) Bend 4|4 E2 Početak 156,320,376 bp Kraj 156,332,073 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GO:0031493 histone binding • nucleosome binding • chromatin binding • GO:0001948, GO:0016582 vezivanje za proteine • GO:0001106 transcription corepressor activity • vezivanje sa RNK Ćelijska komponenta • Noc1p-Noc2p complex • Noc2p-Noc3p complex • Jedarce • jedro • nukleoplazma • citosol Biološki proces • cellular response to UV • negative regulation of B cell apoptotic process • negative regulation of histone acetylation • GO:1901227 negative regulation of transcription by RNA polymerase II • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • negative regulation of intrinsic apoptotic signaling pathway • GO:0097285 apoptoza • ribosomal large subunit biogenesis • regulation of signal transduction by p53 class mediator Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	26155	57741
Ensembl	ENSG00000188976	ENSMUSG00000095567
UniProt	Q9Y3T9	Q9WV70
RefSeq (mRNK)	NM_015658	NM_021303 NM_001369270
RefSeq (bjelančevina)	NP_056473	n/a
Lokacija (UCSC)	Chr 1: 0.94 – 0.96 Mb	Chr 4: 156.32 – 156.33 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 749 aminokiselina, a molekulska težina 84.919 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAAAGSRKRR		LAELTVDEFL		ASGFDSESES		ESENSPQAET		REAREAARSP
DKPGGSPSAS		RRKGRASEHK		DQLSRLKDRD		PEFYKFLQEN		DQSLLNFSDS
DSSEEEEGPF		HSLPDVLEEA		SEEEDGAEEG		EDGDRVPRGL		KGKKNSVPVT
VAMVERWKQA		AKQRLTPKLF		HEVVQAFRAA		VATTRGDQES		AEANKFQVTD
SAAFNALVTF		CIRDLIGCLQ		KLLFGKVAKD		SSRMLQPSSS		PLWGKLRVDI
KAYLGSAIQL		VSCLSETTVL		AAVLRHISVL		VPCFLTFPKQ		CRMLLKRMVI
VWSTGEESLR		VLAFLVLSRV		CRHKKDTFLG		PVLKQMYITY		VRNCKFTSPG
ALPFISFMQW		TLTELLALEP		GVAYQHAFLY		IRQLAIHLRN		AMTTRKKETY
QSVYNWQYVH		CLFLWCRVLS		TAGPSEALQP		LVYPLAQVII		GCIKLIPTAR
FYPLRMHCIR		ALTLLSGSSG		AFIPVLPFIL		EMFQQVDFNR		KPGRMSSKPI
NFSVILKLSN		VNLQEKAYRD		GLVEQLYDLT		LEYLHSQAHC		IGFPELVLPV
VLQLKSFLRE		CKVANYCRQV		QQLLGKVQEN		SAYICSRRQR		VSFGVSEQQA
VEAWEKLTRE		EGTPLTLYYS		HWRKLRDREI		QLEISGKERL		EDLNFPEIKR
RKMADRKDED		RKQFKDLFDL		NSSEEDDTEG		FSERGILRPL		STRHGVEDDE
EDEEEGEEDS		SNSEDGDPDA		EAGLAPGELQ		QLAQGPEDEL		EDLQLSEDD

Dopunska literatura

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