MYBL1

MYBL1
Identifikatori
Aliasi	MYBL1
Vanjski ID-jevi	OMIM: 159405 MGI: 99925 HomoloGene: 32045 GeneCards: MYBL1
Lokacija gena (čovjek)
Hrom.	Hromosom 8 (čovjek)
Kraj	66,614,247 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	9,770,434 bp
Ontologija gena
Molekularna funkcija	• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • vezivanje sa DNK; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• jedro;
Biološki proces	• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • transcription by RNA polymerase II; • GO:0007067 Mitoza; • male meiosis I; • Spermatogeneza; • negative regulation of transposition; • Ćelijska diferencijacija; • piRNA biosynthetic process;
	Izvori:Amigo / QuickGO
Ortolozi
	4603
	17864
	ENSG00000185697
	ENSMUSG00000025912
	P10243
	P51960
	NM_001080416; NM_001144755; NM_001294282
	NM_001290397; NM_008651
	NP_001073885; NP_001138227; NP_001281211
	NP_001277326; NP_032677
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

MYB proto-onkogenoliki protein 1 je protein koji je kod ljudi kodiran genom MYBL1.^[5]

Aminokiselinska sekvenca

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185697 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025912 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: MYB proto-oncogene like 1". Pristupljeno 15. 11. 2016.
^ "UniProt, P10243" (jezik: engleski). Pristupljeno 20. 9. 2021.

Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, Cho YJ, Taha H, Mahmoud M, Bowers DC, Margraf L, Tabori U, Hawkins C, Packer RJ, Hill DA, Pomeroy SL, Eberhart CG, Dunn IF, Goumnerova L, Getz G, Chan JA, Santagata S, Hahn WC, Stiles CD, Ligon AH, Kieran MW, Beroukhim R, Ligon KL (2013). "Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1". Proc. Natl. Acad. Sci. U.S.A. 110 (20): 8188–93. Bibcode:2013PNAS..110.8188R. doi:10.1073/pnas.1300252110. PMC 3657784. PMID 23633565.