IMP4

IMP4
Identifikatori
Aliasi	IMP4
Vanjski ID-jevi	OMIM: 612981 MGI: 106572 HomoloGene: 68891 GeneCards: IMP4
Lokacija gena (čovjek)
Hrom.	Hromosom 2 (čovjek)
Kraj	130,347,967 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	34,488,437 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine; • rRNA primary transcript binding; • snoRNA binding;
Ćelijska komponenta	• small-subunit processome; • Jedarce; • jedro; • nukleoplazma; • fibrillar center; • preribosome; • Mpp10 complex;
Biološki proces	• ribosome biogenesis; • rRNA processing;
	Izvori:Amigo / QuickGO
Ortolozi
	92856
	27993
	ENSG00000136718
	ENSMUSG00000026127
	Q96G21
	Q8VHZ7
NM_033416; NM_001320304; NM_001320305; NM_001320306; NM_001320307;
	NM_001320309; NM_001320310; NM_001320311; NM_001371725; NM_001371726; NM_001371728; NM_001371730; NM_001371731; NM_001371732; NM_001371733; NM_001371734
	NM_178601
NP_001307233; NP_001307234; NP_001307235; NP_001307236; NP_001307238;
	NP_001307239; NP_001307240; NP_219484; NP_001358654; NP_001358655; NP_001358657; NP_001358659; NP_001358660; NP_001358661; NP_001358662; NP_001358663
	NP_848716
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

U3 mali jedarčani ribonukleoproteinski protein IMP4 jest protein koji je kod ljudi kodiran genom IMP4 sa hromosoma 2.^[5]^[6]^[7]

Amiokiselininska sekvenca uredi

Dužina polipeptidnog lanca je 291 aminokiselina, a molekulska težina 33.757 Da.^[8]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MLRREARLRR	EYLYRKAREE	AQRSAQERKE	RLRRALEENR	LIPTELRREA
LALQGSLEFD	DAGGEGVTSH	VDDEYRWAGV	EDPKVMITTS	RDPSSRLKMF
AKELKLVFPG	AQRMNRGRHE	VGALVRACKA	NGVTDLLVVH	EHRGTPVGLI
VSHLPFGPTA	YFTLCNVVMR	HDIPDLGTMS	EAKPHLITHG	FSSRLGKRVS
DILRYLFPVP	KDDSHRVITF	ANQDDYISFR	HHVYKKTDHR	NVELTEVGPR
FELKLYMIRL	GTLEQEATAD	VEWRWHPYTN	TARKRVFLST	E

Reference uredi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136718 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026127 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
^ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
^ "Entrez Gene: IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)".
^ "UniProt, Q96G21" (jezik: engleski). Pristupljeno 17. 11. 2021.

Dopunska literatura uredi

Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Granneman S, Gallagher JE, Vogelzangs J, et al. (2003). "The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes". Nucleic Acids Res. 31 (7): 1877–87. doi:10.1093/nar/gkg300. PMC 152815. PMID 12655004.
Leary DJ, Terns MP, Huang S (2004). "Components of U3 snoRNA-containing complexes shuttle between nuclei and the cytoplasm and differentially localize in nucleoli: implications for assembly and function". Mol. Biol. Cell. 15 (1): 281–93. doi:10.1091/mbc.E03-06-0363. PMC 307547. PMID 14565981.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136718 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026127 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8619474-5] Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

[pmid9110174-6] Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.

[entrez-7] "Entrez Gene: IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)".

[UniProt-8] "UniProt, Q96G21" (jezik: engleski). Pristupljeno 17. 11. 2021.

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