HRSP12
Ribonukleaza UK114 je enzim koji je kod ljudi kodiran genom HRSP12.[5][6][7]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 137 aminokiselina, а molekulska težina 14.494 Da.[8]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MSSLIRRVIS | TAKAPGAIGP | YSQAVLVDRT | IYISGQIGMD | PSSGQLVSGG | ||||
| VAEEAKQALK | NMGEILKAAG | CDFTNVVKTT | VLLADINDFN | TVNEIYKQYF | ||||
| KSNFPARAAY | QVAALPKGSR | IEIEAVAIQG | PLTTASL |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000132541 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022323 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Schmiedeknecht G, Kerkhoff C, Orso E, Stohr J, Aslanidis C, Nagy GM, Knuechel R, Schmitz G (Jan 1997). "Isolation and characterization of a 14.5-kDa trichloroacetic-acid-soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation". Eur J Biochem. 242 (2): 339–51. doi:10.1111/j.1432-1033.1996.0339r.x. PMID 8973653.
- ^ Schmiedeknecht G, Buchler C, Schmitz G (Jan 1998). "A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1". Biochem Biophys Res Commun. 241 (1): 59–67. doi:10.1006/bbrc.1997.7772. PMID 9405234.
- ^ "Entrez Gene: HRSP12 heat-responsive protein 12".
- ^ "UniProt, P52758" (jezik: engleski). Pristupljeno 19. 9. 2021.
Dopunska literatura
uredi- Mistiniene E, Pozdniakovaite N, Popendikyte V, Naktinis V (2006). "Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF". Int. J. Biol. Macromol. 37 (1–2): 61–8. doi:10.1016/j.ijbiomac.2005.08.008. PMID 16198412.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Manjasetty BA, Delbrück H, Pham DT, et al. (2004). "Crystal structure of Homo sapiens protein hp14.5". Proteins. 54 (4): 797–800. doi:10.1002/prot.10619. PMID 14997576. S2CID 723244.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Kanouchi H, Oka T, Asagi K, et al. (2000). "Expression and cellular distribution of perchloric acid-soluble protein is dependent on the cell-proliferating states of NRK-52E cells". Cell. Mol. Life Sci. 57 (7): 1103–8. doi:10.1007/PL00000746. PMID 10961346. S2CID 22844282.
- Morishita R, Kawagoshi A, Sawasaki T, et al. (1999). "Ribonuclease activity of rat liver perchloric acid-soluble protein, a potent inhibitor of protein synthesis". J. Biol. Chem. 274 (29): 20688–92. doi:10.1074/jbc.274.29.20688. PMID 10400702.
- Colombo I, Ceciliani F, Ronchi S, et al. (1998). "cDNA cloning and Escherichia coli expression of UK114 tumor antigen". Biochim. Biophys. Acta. 1442 (1): 49–59. doi:10.1016/s0167-4781(98)00120-1. PMID 9767104.
- Racca S, Di Carlo F, Bartorelli A, et al. (1998). "Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114". Virchows Arch. 431 (5): 323–8. doi:10.1007/s004280050106. PMID 9463573. S2CID 30926226.
- Oka T, Tsuji H, Noda C, et al. (1996). "Isolation and characterization of a novel perchloric acid-soluble protein inhibiting cell-free protein synthesis". J. Biol. Chem. 270 (50): 30060–7. doi:10.1074/jbc.270.50.30060. PMID 8530410.
Vanjski linkovi
uredi- HRSP12 lokacija ljudskog genoma UCSC Genome Browser.
HRSP12 detalji ljudskog genoma u UCSC Genome Browser.