Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 368 aminokiselina , a molekulska težina 41.149 Da .[ 7]
10 20 30 40 50 MAAAAEERMA EEGGGGQGDG GSSLASGSTQ RQPPPPAPQH PQPGSQALPA PALAPDQLPQ NNTLVALPIV AIENILSFMS YDEISQLRLV CKRMDLVCQR MLNQGFLKVE RYHNLCQKQV KAQLPRRESE RRNHSLARHA DILAAVETRL SLLNMTFMKY VDSNLCCFIP GKVIDEIYRV LRYVNSTRAP QRAHEVLQEL RDISSMAMEY FDEKIVPILK RKLPGSDVSG RLMGSPPVPG PSAALTTMQL FSKQNPSRQE VTKLQQQVKT NGAGVTVLRR EISELRTKVQ EQQKQLQDQD QKLLEQTQII GEQNARLAEL ERKLREVMES AVGNSSGSGQ NEESPRKRKK ATEAIDSLRK SKRLRNRK
Članovi porodice proteina F-kutije, kao što je FBXO28, karakteriziraju se približno 40-aminokiselinski motiv F-kutije. SCF kompleksi, formirani od SKP1 (MIM 601434), kulina (vidi CUL1; MIM 603134) i proteina F-kutije, djeluju kao protein-ubikvitin-ligaze . Proteini F-kutije stupaju u interakciju sa SKP1 preko F-kutije, a oni u interakciji sa ciljevima ubikvitinacije preko drugih domena interakcije proteina (Jin et al., 2004, OMIM [ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000143756 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047539 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain" . DNA Res . 4 (5): 345–9. doi :10.1093/dnares/4.5.345 PMID 9455484 . ^ a b "Entrez Gene: FBXO28 F-box protein 28" .^ "UniProt, Q9NVF7" (jezik: en.). Pristupljeno 10. 12. 2021 .CS1 održavanje: nepoznati jezik (link )
Dopunska literatura
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