Redoksregulacijski protein FAM213A, član A porodice proteina sa sličnošću sekvence 213A, znan i kao peroksiredoksinoliki protein 2 aktiviran M-CSF stimuliranim monocitima (PAMM) je protein koji je kod ljudi kodiran genom FAM213A.[5][6]

FAM213A
Identifikatori
AliasiPRXL2A
Vanjski ID-jeviOMIM: 617165 MGI: 1917814 HomoloGene: 12356 GeneCards: PRXL2A
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za FAM213A
Genomska lokacija za FAM213A
Bend10q23.1Početak80,407,829 bp[1]
Kraj80,437,115 bp[1]
Lokacija gena (miš)
Hromosom 14 (miš)
Hrom.Hromosom 14 (miš)[2]
Hromosom 14 (miš)
Genomska lokacija za FAM213A
Genomska lokacija za FAM213A
Bend14|14 BPočetak40,715,697 bp[2]
Kraj40,735,745 bp[2]
Ontologija gena
Molekularna funkcija antioxidant activity
Ćelijska komponenta citoplazma
extracellular region
Biološki proces regulation of osteoclast differentiation
cellular oxidant detoxification
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_001243778
NM_001243779
NM_001243780
NM_001243781
NM_001243782

NM_032333

NM_027464
NM_001316732
NM_001316733
NM_001316734
NM_001316735

NM_001316736
NM_001316737
NM_001316739
NM_001316740
NM_001378813
NM_001378814
NM_001378815

RefSeq (bjelančevina)
NP_001230707
NP_001230708
NP_001230709
NP_001230710
NP_001230711

NP_115709

NP_001303661
NP_001303662
NP_001303663
NP_001303664
NP_001303665

NP_001303666
NP_001303668
NP_001303669
NP_081740
NP_001365742
NP_001365743
NP_001365744

Lokacija (UCSC)Chr 10: 80.41 – 80.44 MbChr 14: 40.72 – 40.74 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 229 aminokiselina, а molekulska težina 25.764 Da.[7]

1020304050
MSFLQDPSFFTMGMWSIGAGALGAAALALLLANTDVFLSKPQKAALEYLE
DIDLKTLEKEPRTFKAKELWEKNGAVIMAVRRPGCFLCREEAADLSSLKS
MLDQLGVPLYAVVKEHIRTEVKDFQPYFKGEIFLDEKKKFYGPQRRKMMF
MGFIRLGVWYNFFRAWNGGFSGNLEGEGFILGGVFVVGSGKQGILLEHRE
KEFGDKVNLLSVLEAAKMIKPQTLASEKK

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122378 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021792 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–1403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
  6. ^ "Entrez Gene: C10orf58 chromosome 10 open reading frame 58".
  7. ^ "UniProt, Q9BRX8". Pristupljeno 1. 9. 2021.

Dopunska literatura

uredi