FAM20B

FAM20B
Identifikatori
Aliasi	FAM20B
Vanjski ID-jevi	OMIM: 611063 MGI: 2443990 HomoloGene: 8909 GeneCards: FAM20B
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	179,076,567 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	156,546,656 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• aktivnost sa transferazom; • nucleotide binding; • ATP binding; • vezivanje iona metala; • phosphotransferase activity, alcohol group as acceptor; • kinase activity; • GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• integral component of membrane; • Golđijeva membrana; • Golđijev aparat; • membrana; • nukleoplazma;
Biološki proces	• Fosforilacija; • protein phosphorylation; • proteoglycan biosynthetic process;
	Izvori:Amigo / QuickGO
Ortolozi
	9917
	215015
	ENSG00000116199
	ENSMUSG00000033557
	O75063
	Q8VCS3
	NM_014864; NM_001324310; NM_001324311
	NM_145413
	NP_001311239; NP_001311240; NP_055679
	NP_663388
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein FAM20B jest protein koji je kod ljudi kodiran genom FAM20B sa hromosoma 1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 409 aminokiselina, a molekulska težina 46.432 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MKLKQRVVLL	AILLVIFIFT	KVFLIDNLDT	SAANREDQRA	FHRMMTGLRV
ELAPKLDHTL	QSPWEIAAQW	VVPREVYPEE	TPELGAVMHA	MATKKIIKAD
VGYKGTQLKA	LLILEGGQKV	VFKPKRYSRD	HVVEGEPYAG	YDRHNAEVAA
FHLDRILGFH	RAPLVVGRFV	NLRTEIKPVA	TEQLLSTFLT	VGNNTCFYGK
CYYCRETEPA	CADGDIMEGS	VTLWLPDVWP	LQKHRHPWGR	TYREGKLARW
EYDESYCDAV	KKTSPYDSGP	RLLDIIDTAV	FDYLIGNADR	HHYESFQDDE
GASMLILLDN	AKSFGNPSLD	ERSILAPLYQ	CCIIRVSTWN	RLNYLKNGVL
KSALKSAMAH	DPISPVLSDP	HLDAVDQRLL	SVLATVKQCT	DQFGMDTVLV
EDRMPLSHL

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116199 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033557 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–349. doi:10.1093/dnares/4.5.345. PMID 9455484.
^ "Entrez Gene: FAM20B family with sequence similarity 20, member B".
^ "UniProt, O75063" (jezik: en.). Pristupljeno 10. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

Baxendale HE, Goldblatt D (2006). "Correlation of molecular characteristics, isotype, and in vitro functional activity of human antipneumococcal monoclonal antibodies". Infect. Immun. 74 (2): 1025–1031. doi:10.1128/IAI.74.2.1025-1031.2006. PMC 1360365. PMID 16428749.
Nalbant D, Youn H, Nalbant SI, et al. (2006). "FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells". BMC Genomics. 6: 11. doi:10.1186/1471-2164-6-11. PMC 548683. PMID 15676076.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yavuz S, Grammer AC, Yavuz AS, et al. (2001). "Comparative characteristics of mu chain and alpha chain transcripts expressed by individual tonsil plasma cells". Mol. Immunol. 38 (1): 19–34. doi:10.1016/S0161-5890(01)00036-0. PMID 11483207.
Baxendale HE, Davis Z, White HN, et al. (2000). "Immunogenetic analysis of the immune response to pneumococcal polysaccharide". Eur. J. Immunol. 30 (4): 1214–1223. doi:10.1002/(SICI)1521-4141(200004)30:4<1214::AID-IMMU1214>3.0.CO;2-D. PMID 10760811.
Ishikawa K, Nagase T, Nakajima D, et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–313. doi:10.1093/dnares/4.5.307. PMID 9455477.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000116199 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033557 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9455484-5] Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–349. doi:10.1093/dnares/4.5.345. PMID 9455484.

[entrez-6] "Entrez Gene: FAM20B family with sequence similarity 20, member B".

[UniProt-7] "UniProt, O75063" (jezik: en.). Pristupljeno 10. 12. 2021.CS1 održavanje: nepoznati jezik (link)

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