Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 904 aminokiseline, а molekulska težina 104.880 Da.[6]
| 10 | | 20 | | 30 | | 40 | | 50 |
|---|
| MESFHTRFSA | | WTPFSNKSLN | | RQLFQERVAL | | ISHWFDLWTN | | KQRQEFLFAI |
| FLRCTKSQLR | | FVQDWFSERM | | QVAKVDFSTV | | LPRFISLYIF | | SFLSPKDLCA |
| AAQVSWPWKF | | LTEQDCLWMP | | KCVKFGWFLP | | YTPTDNEYGA | | WKRHYIACVS |
| HLDWLTPREA | | AATYGTLNEP | | KTEDEELLER | | QREKCLRKRI | | WEKIALRKKE |
| LFKVRPPWVS | | GTCCSSVLKP | | RCQPRLSQTV | | RERVGLHEAL | | EKQLVLTSLE |
| TLPKRSNISG | | SHSYPLLSKK | | NWHGVHKNDD | | RSSYALRPHF | | MLISSRIPAY |
| EMVMESVKAG | | VVSVVYEHSV | | TLESLLYLIE | | KALDGQKAQS | | IGIFSDGDSR |
| EINLLQGYKI | | GVKNLLRPEV | | RDFWEKLGSY | | VATEEEGGHV | | DFFVPLGASE |
| AGIEVLSQLS | | QLTGTFFTAP | | TGIATGSYQH | | ILSDWLGSQW | | GKAPSSIYFC |
| ESKLQTWSSF | | TDFLEETLKT | | VRKQLYPFFK | | ELQKSISGRM | | IGQFMFDTMG |
| MTNILNNQDT | | AQALADGLME | | LSKEDSERNV | | VEDNSWDTKS | | RLSKNDLNFE |
| ALINLERILQ | | KDSAEKRARV | | VRELLQSERK | | YVQILEIVRD | | VYVAPLKAAL |
| SSNRAILSAA | | NIQIIFCDIL | | QILSLNRQFL | | DNLRDRLQEW | | GPAHCVGEIV |
| TKFGSQLNTY | | TNFFNNYPVI | | LKTIEKCREM | | IPAFRTFLKR | | HDKTIVTKML |
| SLPELLLYPS | | RRFEEYLNLL | | YAVRLHTPAE | | HVDRGDLTTA | | IDQIKKYKGY |
| IDQMKQNITM | | KDHLSDIQRI | | IWGCPTLSEV | | NRYLIRVQDV | | AQLHCCDEEI |
| SFSLRLYEHI | | HDLSLFLFND | | ALLVSSRGTS | | HTPFERTSKT | | TYQFIASVAL |
| HRLLIENIPD | | SKYVKNAFIL | | QGPKYKWICA | | TEIEDDKFLW | | LSVLRNAIKS |
| SMEK |
Klinička važnost
uredi
- ^ a b c GRCh38: Ensembl release 89: ENSG00000203734 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071392 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Epithelial cell transforming sequence 2 oncogene-like". Pristupljeno 19. 2. 2012.
- ^ "UniProt, Q008S8" (jezik: engleski). Pristupljeno 7. 10. 2021.
- ^ Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG (2012). "The genetic basis of early T-cell precursor acute lymphoblastic leukaemia". Nature. 481 (7380): 157–163. Bibcode:2012Natur.481..157Z. doi:10.1038/nature10725. PMC 3267575. PMID 22237106.
