Dihidropirimidinazi srodni protein 4 je enzim koji je kod ljudi kodiran genom DPYSL4.[5][6][7]

DPYSL4
Identifikatori
AliasiDPYSL4
Vanjski ID-jeviOMIM: 608407 MGI: 1349764 HomoloGene: 4691 GeneCards: DPYSL4
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za DPYSL4
Genomska lokacija za DPYSL4
Bend10q26.3Početak132,186,948 bp[1]
Kraj132,205,759 bp[1]
Lokacija gena (miš)
Hromosom 7 (miš)
Hrom.Hromosom 7 (miš)[2]
Hromosom 7 (miš)
Genomska lokacija za DPYSL4
Genomska lokacija za DPYSL4
Bend7|7 F4Početak138,665,917 bp[2]
Kraj138,682,620 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
filamin binding
Ćelijska komponenta citoplazma
citosol
Biološki proces neuron death
neuron projection guidance
nervous system development
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_006426

NM_011993

RefSeq (bjelančevina)

NP_006417

n/a

Lokacija (UCSC)Chr 10: 132.19 – 132.21 MbChr 7: 138.67 – 138.68 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 572 aminokiseline, а molekulska težina 61.878.[8]

1020304050
MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLI
VPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGG
TTMILDHVFPDTGVSLLAAYEQWRERADSAACCDYSLHVDITRWHESIKE
ELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIRDLGALAQVHAE
NGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPL
YVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAA
FVTSPPVNPDPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFAL
IPEGTNGIEERMSMVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGR
VAVGSDADLVIWNPKATKIISAKTHNLNVEYNIFEGVECRGAPAVVISQG
RVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLAEIHGVPRGLYD
GPVHEVMVPAKPGSGAPARASCPGKISVPPVRNLHQSGFSLSGSQADDHI
ARRTAQKIMAPPGGRSNITSLS

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000151640 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025478 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M (Jan 1997). "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution". Gene. 180 (1–2): 157–63. doi:10.1016/S0378-1119(96)00445-3. PMID 8973361.
  6. ^ Byk T, Ozon S, Sobel A (Jul 1998). "The Ulip family phosphoproteins--common and specific properties". Eur J Biochem. 254 (1): 14–24. doi:10.1046/j.1432-1327.1998.2540014.x. PMID 9652388.
  7. ^ "Entrez Gene: DPYSL4 dihydropyrimidinase-like 4".
  8. ^ "UniProt, O14531". Pristupljeno 1. 9. 2021.

Dopunska literatura

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Vanjski linkovi

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