ATP5SL

ATP5SL
Identifikatori
Aliasi	DMAC2
Vanjski ID-jevi	OMIM: 617262 MGI: 1913599 HomoloGene: 9973 GeneCards: DMAC2
Lokacija gena (čovjek)
Hrom.	Hromosom 19 (čovjek)
Kraj	41,440,717 bp
Lokacija gena (miš)
Hrom.	Hromosom 7 (miš)
Kraj	25,324,976 bp
Ontologija gena
Molekularna funkcija	• GO:0050372 aktivnost sa transferazom ubikvitina;
Ćelijska komponenta	• mitohondrija; • mitochondrial respiratory chain complex I; • SCF ubiquitin ligase complex;
Biološki proces	• mitochondrial respiratory chain complex I assembly; • ubiquitin-dependent protein catabolic process; • protein ubiquitination; • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;
	Izvori:Amigo / QuickGO
Ortolozi
	55101
	66349
	ENSG00000105341
	ENSMUSG00000057229
	Q9NW81
	Q9D7K5
NM_001167867; NM_001167868; NM_001167869; NM_001167870; NM_001167871;
	NM_018035; NM_001320838; NM_001320839; NM_001320840; NM_001320841; NM_001320844
	NM_001290487; NM_025504
NP_001161339; NP_001161340; NP_001161341; NP_001161342; NP_001161343;
	NP_001307767; NP_001307768; NP_001307769; NP_001307770; NP_001307773; NP_060505
	NP_001277416; NP_079780
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein s-olike podjedinice ATP sintaze je protein koji je kod ljudi kodiran genom ATP5SL.^[5]

Mitohondrijski kompleks I je struktura u obliku čizme, od približno 1 MDa, koji ima hidrofilni matriksni krak i hidrofobni membranski krak. Ljudski kompleks I sadrži 45 podjedinica, od kojih je 14 neophodno za enzimsku funkciju i konzerviran je se od čovjeka do bakterija. Ostalih 31, uključujući ATP5SL, su pomoćne podjedinice.

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10	20	30	40	50
MAAPWASLRL	VAPMWNGRIR	GIHRLGAAVA	PEGNQKKKRT	ILQFLTNYFY
DVEALRDYLL	QREMYKVHEK	NRSYTWLEKQ	HGPYGAGAFF	ILKQGGAVKF
RDKEWIRPDK	YGHFSQEFWN	FCEVPVEAVD	AGDCDINYEG	LDNLLRLKEL
QSLSLQRCCH	VDDWCLSRLY	PLADSLQELS	LAGCPRISER	GLACLHHLQN
LRRLDISDLP	AVSNPGLTQI	LVEEMLPNCE	VVGVDWAEGL	KSGPEEQPRD
TASPVPA

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105341 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000057229 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ATP5S-like".

Vanjski linkovi

Lokacija ljudskog genoma ATP5SL i stranica sa detaljima o genu ATP5SL u UCSC Genome Browseru.

Dopunska literatura

Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105341 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000057229 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ATP5S-like".

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