Navodna ATP-ovisna RNK-helikaza DHX57 jest enzim koji je kod ljudi kodiran genom DHX57 sa hromosoma 2.[5]

DHX57
Identifikatori
AliasiDHX57
Vanjski ID-jeviMGI: 2147067 HomoloGene: 56267 GeneCards: DHX57
Lokacija gena (čovjek)
Hromosom 2 (čovjek)
Hrom.Hromosom 2 (čovjek)[1]
Hromosom 2 (čovjek)
Genomska lokacija za DHX57
Genomska lokacija za DHX57
Bend2p22.1Početak38,797,729 bp[1]
Kraj38,875,934 bp[1]
Lokacija gena (miš)
Hromosom 17 (miš)
Hrom.Hromosom 17 (miš)[2]
Hromosom 17 (miš)
Genomska lokacija za DHX57
Genomska lokacija za DHX57
Bend17|17 E3Početak80,238,309 bp[2]
Kraj80,290,476 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija nucleotide binding
GO:0001948, GO:0016582 vezivanje za proteine
hydrolase activity
ATP binding
GO:0008026 helicase activity
vezivanje iona metala
nucleic acid binding
vezivanje sa RNK
GO:0034459 3'-5' RNA helicase activity
Ćelijska komponenta mitohondrija
Biološki proces GO:0033168, GO:0036404, GO:1902360 RNA processing
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_198963
NM_001329963
NM_144995
NM_145646

NM_001163759
NM_198942

RefSeq (bjelančevina)

NP_001316892
NP_945314
NP_945314.1

NP_001157231
NP_945180

Lokacija (UCSC)Chr 2: 38.8 – 38.88 MbChr 17: 80.24 – 80.29 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Amiokiselininska sekvenca

uredi

Dužina polipeptidnog lanca je 1.386 aminokiselina, a molkekulska iežina 155.604 Da.[6]

1020304050
MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN
RKASSRIWDDGDDFCIFSESRRPSRPSNSNISKGESRPKWKPKAKVPLQT
LHMTSENQEKVKALLRDLQEQDADAGSERGLSGEEEDDEPDCCNDERYWP
AGQEPSLVPDLDPLEYAGLASVEPYVPEFTVSPFAVQKLSRYGFNTERCQ
AVLRMCDGDVGASLEHLLTQCFSETFGERMKISEAVNQISLDECMEQRQE
EAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQEN
SLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDAS
FLYELEIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTF
AETSEPVVYSLITLLEEESEIVKLLTNTHHKYSDPPVNFLPVPSRTRINN
PACHKTVIPNNSFVSNQIPEVEKASESEESDEDDGPAPVIVENESYVNLK
KKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQERQSLPAWEER
ETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQ
PRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLL
RRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMS
ATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYM
RSMKQISKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDF
KQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAI
LVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFV
KPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLED
TFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLE
QLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDE
RLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSP
WDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNF
LSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATG
EEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSA
ELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMV
SVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCE
LDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163214 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035051 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57".
  6. ^ "UniProt, Q6P158" (jezik: engleski). Pristupljeno 12. 11. 2021.

Dopunska literatura

uredi

Vanjski linkovi

uredi