DFNA5

DFNA5
Identifikatori
Aliasi	GSDME
Vanjski ID-jevi	OMIM: 608798 MGI: 1889850 HomoloGene: 3242 GeneCards: GSDME
Lokacija gena (čovjek)
Hrom.	Hromosom 7 (čovjek)
Kraj	24,757,940 bp
Lokacija gena (miš)
Hrom.	Hromosom 6 (miš)
Kraj	50,240,842 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• phosphatidylinositol-4,5-bisphosphate binding; • cardiolipin binding;
Ćelijska komponenta	• citoplazma; • citosol; • ćelijska membrana; • membrana;
Biološki proces	• inner ear receptor cell differentiation; • sensory perception of sound; • positive regulation of intrinsic apoptotic signaling pathway; • negative regulation of cell population proliferation; • GO:0010703, GO:0010702 programirana ćelijska smrt; • Ćelijska smrt; • positive regulation of MAPK cascade; • necrotic cell death; • Piroptoza; • cellular response to tumor necrosis factor; • cellular response to virus;
	Izvori:Amigo / QuickGO
Ortolozi
	1687
	54722
	ENSG00000105928
	ENSMUSG00000029821
	O60443
	Q9Z2D3
	NM_004403; NM_001127453; NM_001127454
	NM_018769
	NP_001120925; NP_001120926; NP_004394; NP_001120926.1
	NP_061239
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Gasdermin C jest protein koji je kod ljudi kodiran genom GSDMC sa hromosoma 8.^[5]

Aminokiselinska sekvenca uredi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105928 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029821 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: Gasdermin C". Pristupljeno 26. 8. 2016.

Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310. S2CID 19705164.