CNST

CNST
Identifikatori
Aliasi	CNST
Vanjski ID-jevi	OMIM: 613439 MGI: 2445141 HomoloGene: 17139 GeneCards: CNST
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	246,668,595 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	179,455,043 bp
Obrazac RNK ekspresije
	; ; ; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• phosphatase binding; • GO:0001948, GO:0016582 vezivanje za proteine; • connexin binding;
Ćelijska komponenta	• integral component of membrane; • trans-Golđijeva mreža; • ćelijska membrana; • Golđijev aparat; • transport vesicle; • membrana; • GO:0016023 citoplazmatska vezikula; • intracellular membrane-bounded organelle; • GO:0009327 makromolekulani kompleks;
Biološki proces	• negative regulation of phosphatase activity; • positive regulation of Golgi to plasma membrane protein transport;
	Izvori:Amigo / QuickGO
Ortolozi
	163882
	226744
	ENSG00000162852
	ENSMUSG00000038949
	Q6PJW8
	Q8CBC4
	NM_001139459; NM_152609
	NM_146105
	NP_001132931; NP_689822
	NP_666217
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Konsortin (CNST) jest protein koji je kod ljudi kodiran genom CNST sa hromosoma 1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 725 aminokiselina, a molekulska težina 79.597 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MDDSDTPTYY	LQIEPQDGCH	PGDSVERSVT	CLPSASDENE	NQLDGDGHEH
LTSSDSAMGK	PQVSEQDSLN	NNESCTLSCE	VAAGENLQNT	LCEASRDEQA
FLGKDKKIPG	KRSPRSKKGT	AKKIPPGLFS	GDIAPLMQEK	VLSAVTYAVD
DEEAAEVNAN	EQPEAPKLVL	QSLFSLIRGE	VEQLDSRALP	LCLHQIAESY
FQEEDYEKAM	KFIQLERLYH	EQLLANLSAI	QEQWETKWKT	VQPHTVTALR
NSEKGFNGED	FERLTKICAT	HQDPLLSKHK	IAAVEKSQER	KCSTQLLVSE
DPKEGGATTK	ESESKTCLGT	ESSKESQHTV	EPLGSSPCCH	QMDVQTDSPS
LSVTAGKDHM	EELLCSAEAT	LALHTQSSET	AGSPSGPDSS	EDACEDDSRL
QLAQTEACQD	VARIEGIAED	PKVFLSSKSK	TEPLISPGCD	RIPPALISEG
KYSQAQRKEL	RLPLRDASEA	LPTDQLENNE	LNELQQPDLT	DSDGKSPQAQ
ADSDGSENVL	CGNNQISDLG	ILLPEVCMAP	EEKGDKDDQL	NKETEDYLNS
LLEGCLKDTE	DSLSYEDNQD	DDSDLLQDLS	PEEASYSLQE	NLPSDESCLS
LDDLAKRIEI	AEVVPTEGLV	SILKKRNDTV	GDHPAQMQHK	PSKRRVRFQE
IDDSLDQDEV	GGGSCILLVL	LCIATVFLSV	GGTALYCTFG	DMESPVCTDF
ADNMDFYYTK	LLQGVAELKH	WIYLS

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162852 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038949 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
^ "Entrez Gene: C1orf71 chromosome 1 open reading frame 71".
^ "UniProt, Q6PJW8" (jezik: en.). Pristupljeno 9. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162852 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038949 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: C1orf71 chromosome 1 open reading frame 71".

[UniProt-7] "UniProt, Q6PJW8" (jezik: en.). Pristupljeno 9. 12. 2021.CS1 održavanje: nepoznati jezik (link)

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