Otvoreni okvir čitanja 109 hromosoma 1 jest protein koji je kod ljudi kodiran genom C1orf109 sa hromosoma 1.[4]

C1orf109
Identifikatori
AliasiC1orf109
Vanjski ID-jeviOMIM: 614799 MGI: 3041172 HomoloGene: 23053 GeneCards: C1orf109
Lokacija gena (miš)
Hromosom 4 (miš)
Hrom.Hromosom 4 (miš)[1]
Hromosom 4 (miš)
Genomska lokacija za C1orf109
Genomska lokacija za C1orf109
Bend4|4 D2.2Početak124,830,841 bp[1]
Kraj124,838,449 bp[1]
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001303030
NM_001303031
NM_017850

NM_177573
NM_001355603
NM_001355605

RefSeq (bjelančevina)
NP_001289959
NP_001289960
NP_060320
NP_001337684
NP_001337685

NP_001337686
NP_001337687
NP_001337688
NP_001337689
NP_001337690
NP_001337691
NP_001337692
NP_001337693
NP_001337694
NP_001337695
NP_001337696
NP_001337697
NP_001337698
NP_001337699
NP_001337700

NP_808241
NP_001342532
NP_001342534

Lokacija (UCSC)n/aChr 4: 124.83 – 124.84 Mb
PubMed pretraga[2][3]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Amiokiselininska sekvenca

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Dužina polipeptidnog lanca je 203 aminokiseline, a molekulska težina 23.373 Da.[5]

1020304050
MTQDRPLLAVQEALKKCFPVVEEQQGLWQSALRDCQPLLSSLSNLAEQLQ
AAQNLRFEDVPALRAFPDLKERLRRKQLVAGDIVLDKLGERLAILLKVRD
MVSSHVERVFQIYEQHADTVGIDAVLQPSAVSPSVADMLEWLQDIERHYR
KSYLKRKYLLSSIQWGDLANIQALPKAWDRISKDEHQDLVQDILLNVSFF
LEE

Klinički značaj

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Ovaj gen može igrati ulogu u proliferaciji ćelija raka.[6]

Reference

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044730 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Entrez Gene: Chromosome 1 open reading frame 109". Pristupljeno 30. 10. 2012.
  5. ^ "UniProt, Q9NX04" (jezik: engleski). Pristupljeno 22. 11. 2021.
  6. ^ Liu SS, Zheng HX, Jiang HD, He J, Yu Y, Qu YP, Yue L, Zhang Y, Li Y (2012). "Identification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation". J. Biomed. Sci. 19: 49. doi:10.1186/1423-0127-19-49. PMC 3546425. PMID 22548824.

Vanjski linkovi

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