Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 419 aminokiselina , а molekulska težina 46.533 Da .[ 4]
10 20 30 40 50
MPGRGRCPDC GSTELVEDSH YSQSQLVCSD CGCVVTEGVL TTTFSDEGNL
REVTYSRSTG ENEQVSRSQQ RGLRRVRDLC RVLQLPPTFE DTAVAYYQQA
YRHSGIRAAR LQKKEVLVGC CVLITCRQHN WPLTMGAICT LLYADLDVFS
STYMQIVKLL GLDVPSLCLA ELVKTYCSSF KLFQASPSVP AKYVEDKEKM
LSRTMQLVEL ANETWLVTGR HPLPVITAAT FLAWQSLQPA DRLSCSLARF
CKLANVDLPY PASSRLQELL AVLLRMAEQL AWLRVLRLDK RSVVKHIGDL
LQHRQSLVRS AFRDGTAEVE TREKEPPGWG QGQGEGEVGN NSLGLPQGKR
PASPALLLPP CMLKSPKRIC PVPPVSTVTG DENISDSEIE QYLRTPQEVR
DFQRAQAARQ AATSVPNPP
^ Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs" . Genome Res . 11 (8): 1392–403. doi :10.1101/gr.175501 . PMC 311073 . PMID 11483580 .
^ Cabart P, Murphy S (Nov 2001). "BRFU, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with TATA-binding protein" . J Biol Chem . 276 (46): 43056–64. doi :10.1074/jbc.M108515200 . PMID 11564744 .
^ a b "Entrez Gene: BRF2 BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like" .
^ "UniProt, Q9HAW0" . Pristupljeno 14. 9. 2021 .
Dopunska literatura
uredi
Sutcliffe JE, Cairns CA, McLees A, et al. (1999). "RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130" . Mol. Cell. Biol . 19 (6): 4255–61. doi :10.1128/mcb.19.6.4255 . PMC 104385 . PMID 10330166 .
Schramm L, Pendergrast PS, Sun Y, Hernandez N (2000). "Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters" . Genes Dev . 14 (20): 2650–63. doi :10.1101/gad.836400 . PMC 316990 . PMID 11040218 .
Teichmann M, Wang Z, Roeder RG (2001). "A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements" . Proc. Natl. Acad. Sci. U.S.A . 97 (26): 14200–5. doi :10.1073/pnas.97.26.14200 . PMC 18895 . PMID 11121026 .
Hinkley CS, Hirsch HA, Gu L, et al. (2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition" . J. Biol. Chem . 278 (20): 18649–57. doi :10.1074/jbc.M204247200 . PMID 12621023 .
Saxena A, Ma B, Schramm L, Hernandez N (2005). "Structure-function analysis of the human TFIIB-related factor II protein reveals an essential role for the C-terminal domain in RNA polymerase III transcription" . Mol. Cell. Biol . 25 (21): 9406–18. doi :10.1128/MCB.25.21.9406-9418.2005 . PMC 1265830 . PMID 16227591 .