ZNF408

Protein cinkovog prsta 408 je protein koji je kod ljudi kodiran genom ZNF408.

ZNF408
Identifikatori
Aliasi	ZNF408
Vanjski ID-jevi	OMIM: 616454 MGI: 2685857 HomoloGene: 11687 GeneCards: ZNF408
Lokacija gena (čovjek) Hrom. Hromosom 11 (čovjek) Bend 11p11.2 Početak 46,701,030 bp Kraj 46,705,912 bp
Lokacija gena (miš) Hrom. Hromosom 2 (miš) Bend 2|2 E1 Početak 91,474,014 bp Kraj 91,480,136 bp
Ontologija gena Molekularna funkcija • vezivanje sa DNK • GO:0001948, GO:0016582 vezivanje za proteine • vezivanje iona metala • vezivanje identičnih proteina • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • jedro Biološki proces • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	79797	381410
Ensembl	ENSG00000175213	ENSMUSG00000075040
UniProt	Q9H9D4	n/a
RefSeq (mRNK)	NM_024741 NM_001184751	NM_001033451 NM_001347175
RefSeq (bjelančevina)	NP_001171680 NP_079017	n/a
Lokacija (UCSC)	Chr 11: 46.7 – 46.71 Mb	Chr 2: 91.47 – 91.48 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 720 aminokiselina, a molekulska težina 78.439 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MEEAEELLLE		GKKALQLARE		PRLGLDLGWN		PSGEGCTQGL		KDVPPEPTRD
ILALKSLPRG		LALGPSLAKE		QRLGVWCVGD		PLQPGLLWGP		LEEESASKEK
GEGVKPRQEE		NLSLGPWGDV		CACEQSSGWT		SLVQRGRLES		EGNVAPVRIS
ERLHLQVYQL		VLPGSELLLW		PQPSSEGPSL		TQPGLDKEAA		VAVVTEVESA
VQQEVASPGE		DAAEPCIDPG		SQSPSGIQAE		NMVSPGLKFP		TQDRISKDSQ
PLGPLLQDGD		VDEECPAQAQ		MPPELQSNSA		TQQDPDGSGA		SFSSSARGTQ
PHGYLAKKLH		SPSDQCPPRA		KTPEPGAQQS		GFPTLSRSPP		GPAGSSPKQG
RRYRCGECGK		AFLQLCHLKK		HAFVHTGHKP		FLCTECGKSY		SSEESFKAHM
LGHRGVRPFP		CPQCDKAYGT		QRDLKEHQVV		HSGARPFACD		QCGKAFARRP
SLRLHRKTHQ		VPAAPAPCPC		PVCGRPLANQ		GSLRNHMRLH		TGEKPFLCPH
CGRAFRQRGN		LRGHLRLHTG		ERPYRCPHCA		DAFPQLPELR		RHLISHTGEA
HLCPVCGKAL		RDPHTLRAHE		RLHSGERPFP		CPQCGRAYTL		ATKLRRHLKS
HLEDKPYRCP		TCGMGYTLPQ		SLRRHQLSHR		PEAPCSPPSV		PSAASEPTVV
LLQAEPQLLD		THREEEVSPA		RDVVEVTISE		SQEKCFVVPE		EPDAAPSLVL
IHKDMGLGAW		AEVVEVEMGT

Dopunska literatura

• Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H (februar 2009). "Protein microarray analysis identifies human cellular prion protein interactors". Neuropathology and Applied Neurobiology. 35 (1): 16–35. doi:10.1111/j.1365-2990.2008.00947.x. PMID 18482256. S2CID 32299311.
• Gao J, Li WX, Feng SQ, Yuan YS, Wan DF, Han W, Yu Y (april 2008). "A protein-protein interaction network of transcription factors acting during liver cell proliferation". Genomics. 91 (4): 347–55. doi:10.1016/j.ygeno.2007.12.007. PMID 18255255.
• Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG (novembar 2009). "Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies". Nature Genetics. 41 (11): 1199–206. doi:10.1038/ng.446. PMC 2783489. PMID 19801982.