YTHDC2
Protein 2 sa YTH domenom je protein koji je kod ljudi kodiran genom YTHDC2.[5]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 1.430 aminokiselina, a molekulska težina 160.248 Da.[6]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MSRPSSVSPR | QPAPGGGGGG | GPSPCGPGGG | GRAKGLKDIR | IDEEVKIAVN | ||||
| IALERFRYGD | QREMEFPSSL | TSTERAFIHR | LSQSLGLVSK | SKGKGANRYL | ||||
| TVKKKDGSET | AHAMMTCNLT | HNTKHAVRSL | IQRFPVTNKE | RTELLPKTER | ||||
| GNVFAVEAEN | REMSKTSGRL | NNGIPQIPVK | RGESEFDSFR | QSLPVFEKQE | ||||
| EIVKIIKENK | VVLIVGETGS | GKTTQIPQFL | LDDCFKNGIP | CRIFCTQPRR | ||||
| LAAIAVAERV | AAERRERIGQ | TIGYQIRLES | RVSPKTLLTF | CTNGVLLRTL | ||||
| MAGDSTLSTV | THVIVDEVHE | RDRFSDFLLT | KLRDLLQKHP | TLKLILSSAA | ||||
| LDVNLFIRYF | GSCPVIYIQG | RPFEVKEMFL | EDILRTTGYT | NKEMLKYKKE | ||||
| KQQEEKQQTT | LTEWYSAQEN | SFKPESQRQR | TVLNVTDEYD | LLDDGGDAVF | ||||
| SQLTEKDVNC | LEPWLIKEMD | ACLSDIWLHK | DIDAFAQVFH | LILTENVSVD | ||||
| YRHSETSATA | LMVAAGRGFA | SQVEQLISMG | ANVHSKASNG | WMALDWAKHF | ||||
| GQTEIVDLLE | SYSATLEFGN | LDESSLVQTN | GSDLSAEDRE | LLKAYHHSFD | ||||
| DEKVDLDLIM | HLLYNICHSC | DAGAVLIFLP | GYDEIVGLRD | RILFDDKRFA | ||||
| DSTHRYQVFM | LHSNMQTSDQ | KKVLKNPPAG | VRKIILSTNI | AETSITVNDV | ||||
| VFVIDSGKVK | EKSFDALNFV | TMLKMVWISK | ASAIQRKGRA | GRCRPGICFR | ||||
| LFSRLRFQNM | LEFQTPELLR | MPLQELCLHT | KLLAPVNCPI | ADFLMKAPEP | ||||
| PPALIVRNAV | QMLKTIDAMD | TWEDLTELGY | HLADLPVEPH | LGKMVLCAVV | ||||
| LKCLDPILTI | ACTLAYRDPF | VLPTQASQKR | AAMLCRKRFT | AGAFSDHMAL | ||||
| LRAFQAWQKA | RSDGWERAFC | EKNFLSQATM | EIIIGMRTQL | LGQLRASGFV | ||||
| RARGGGDIRD | VNTNSENWAV | VKAALVAGMY | PNLVHVDREN | LVLTGPKEKK | ||||
| VRFHPASVLS | QPQYKKIPPA | NGQAAAIKAL | PTDWLIYDEM | TRAHRIANIR | ||||
| CCSAVTPVTI | LVFCGPARLA | SNALQEPSSF | RVDGIPNDSS | DSEMEDKTTA | ||||
| NLAALKLDEW | LHFTLEPEAA | SLLLQLRQKW | HSLFLRRMRA | PSKPWSQVDE | ||||
| ATIRAIIAVL | STEEQSAGLQ | QPSGIGQRPR | PMSSEELPLA | SSWRSNNSRK | ||||
| SSADTEFSDE | CTTAERVLMK | SPSPALHPPQ | KYKDRGILHP | KRGTEDRSDQ | ||||
| SSLKSTDSSS | YPSPCASPSP | PSSGKGSKSP | SPRPNMPVRY | FIMKSSNLRN | ||||
| LEISQQKGIW | STTPSNERKL | NRAFWESSIV | YLVFSVQGSG | HFQGFSRMSS | ||||
| EIGREKSQDW | GSAGLGGVFK | VEWIRKESLP | FQFAHHLLNP | WNDNKKVQIS | ||||
| RDGQELEPLV | GEQLLQLWER | LPLGEKNTTD |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000047188 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034653 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: YTH domain containing 2".
- ^ "UniProt, Q9H6S0" (jezik: engleski). Pristupljeno 13. 10. 2021.
Dopunska literatura
uredi- Bhatnagar P, Purvis S, Barron-Casella E, DeBaun MR, Casella JF, Arking DE, Keefer JR (april 2011). "Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients". Journal of Human Genetics. 56 (4): 316–23. doi:10.1038/jhg.2011.12. PMC 5825003. PMID 21326311.
- Morohashi K, Sahara H, Watashi K, Iwabata K, Sunoki T, Kuramochi K, Takakusagi K, Miyashita H, Sato N, Tanabe A, Shimotohno K, Kobayashi S, Sakaguchi K, Sugawara F (april 2011). Klein R (ured.). "Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B". PLOS ONE. 6 (4): e18285. doi:10.1371/journal.pone.0018285. PMC 3084704. PMID 21559518.
- Gano JJ, Simon JA (februar 2010). "A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein". Molecular & Cellular Proteomics. 9 (2): 255–70. doi:10.1074/mcp.M900261-MCP200. PMC 2830838. PMID 19875381.