URG4

Nadregulirani gen 4, znan i kao URG4, jest ljudski gen.

URG4
Identifikatori
Aliasi	URGCP
Vanjski ID-jevi	OMIM: 610337 MGI: 1919296 HomoloGene: 69243 GeneCards: URGCP
Lokacija gena (čovjek) Hrom. Hromosom 7 (čovjek) Bend 7p13 Početak 43,875,894 bp Kraj 43,926,411 bp
Lokacija gena (miš) Hrom. Hromosom 11 (miš) Bend 11|11 A1 Početak 5,663,417 bp Kraj 5,712,376 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GTP binding Ćelijska komponenta • citoplazma • jedro • citosol Biološki proces • ćelijski ciklus Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	55665	72046
Ensembl	ENSG00000106608	ENSMUSG00000049680
UniProt	Q8TCY9	Q5NCI0
RefSeq (mRNK)	NM_017920 NM_001077663 NM_001077664 NM_001290075 NM_001290076	NM_001077661 NM_178623 NM_001361588 NM_001361589 NM_001361590 NM_001361591 NM_001361592
RefSeq (bjelančevina)	NP_001071131 NP_001071132 NP_001277004 NP_001277005 NP_060390	NP_001071129 NP_848738 NP_001348517 NP_001348518 NP_001348519 NP_001348520 NP_001348521
Lokacija (UCSC)	Chr 7: 43.88 – 43.93 Mb	Chr 11: 5.66 – 5.71 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina nukleotidnog lanca je 931 aminokiselina, а molekulska težina 104.987 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MASPGIEVEL		LGKGHSDLGE		VAPEIKASER		RTAVAIADLE		WREMEGDDCE
FRYGDGTNEA		QDNDFPTVER		SRLQEMLSLL		GLETYQVQKL		SLQDSLQISF
DSMKNWAPQV		PKDLPWNFLR		KLQALNADAR		NTTMVLDVLP		DARPVEKESQ
MEEEIIYWDP		ADDLAADIYS		FSELPTPDTP		VNPLDLLCAL		LLSSDSFLQQ
EIALKMALCQ		FALPLVLPDS		ENHYHTFLLW		AMRGIVRTWW		SQPPRGMGSF
REDSVVLSRA		PAFAFVRMDV		SSNSKSQLLN		AVLSPGHRQW		DCFWHRDLNL
GTNAREISDG		LVEISWFFPS		GREDLDIFPE		PVAFLNLRGD		IGSHWLQFKL
LTEISSAVFI		LTDNISKKEY		KLLYSMKEST		TKYYFILSPY		RGKRNTNLRF
LNKLIPVLKI		DHSHVLVKVS		STDSDSFVKR		IRAIVGNVLR		APCRRVSVED
MAHAARKLGL		KVDEDCEECQ		KAKDRMERIT		RKIKDSDAYR		RDELRLQGDP
WRKAAQVEKE		FCQLQWAVDP		PEKHRAELRR		RLLELRMQQN		GHDPSSGVQE
FISGISSPSL		SEKQYFLRWM		EWGLARVAQP		RLRQPPETLL		TLRPKHGGTT
DVGEPLWPEP		LGVEHFLREM		GQFYEAESCL		VEAGRLPAGQ		RRFAHFPGLA
SELLLTGLPL		ELIDGSTLSM		PVRWVTGLLK		ELHVRLERRS		RLVVLSTVGV
PGTGKSTLLN		TMFGLRFATG		KSCGPRGAFM		QLITVAEGFS		QDLGCDHILV
IDSGGLIGGA		LTSAGDRFEL		EASLATLLMG		LSNVTVISLA		ETKDIPAAIL
HAFLRLEKTG		HMPNYQFVYQ		NLHDVSVPGP		RPRDKRQLLD		PPGDLSRAAA
QMEKQGDGFR		ALAGLAFCDP		EKQHIWHIPG		LWHGAPPMAA		VSLAYSEAIF
ELKRCLLENI		RNGLSNQNKN		IQQLIELVRR		L

Dopunska literatura

• Song J, Xie H, Lian Z, Yang G, Du R, Du Y, Zou X, Jin H, Gao J, Liu J, Fan D (decembar 2006). "Enhanced cell survival of gastric cancer cells by a novel gene URG4". Neoplasia. 8 (12): 995–1002. doi:10.1593/neo.06592. PMC 1783723. PMID 17217616.
• Tsang HT, Connell JW, Brown SE, Thompson A, Reid E, Sanderson CM (septembar 2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941.
• Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (august 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL (juli 2004). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics. 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218.
• Tufan NL, Lian Z, Liu J, Pan J, Arbuthnot P, Kew M, Clayton MM, Zhu M, Feitelson MA (2003). "Hepatitis Bx antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survival". Neoplasia. 4 (4): 355–68. doi:10.1038/sj.neo.7900241. PMC 1531705. PMID 12082552.
• Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (april 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.