TP53I11

TP53I11
Identifikatori
Aliasi	TP53I11
Vanjski ID-jevi	OMIM: 617867 MGI: 2670995 HomoloGene: 4404 GeneCards: TP53I11
Lokacija gena (čovjek)
Hrom.	Hromosom 11 (čovjek)
Kraj	44,951,306 bp
Lokacija gena (miš)
Hrom.	Hromosom 2 (miš)
Kraj	93,032,104 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ortolozi
	9537
	277414
	ENSG00000175274
	ENSMUSG00000068735
	O14683
	Q4QQM4
NM_001076787; NM_001258320; NM_001258321; NM_001258322; NM_001258323;
	NM_001258324; NM_006034; NM_001318384; NM_001318385; NM_001318386; NM_001318387; NM_001318388; NM_001318389; NM_001318390
	NM_001025246; NM_001356535; NM_001356536; NM_001356537
NP_001245249; NP_001245250; NP_001245251; NP_001245252; NP_001245253;
	NP_001305313; NP_001305314; NP_001305315; NP_001305316; NP_001305317; NP_001305318; NP_001305319; NP_006025
	NP_001020417; NP_001343464; NP_001343465; NP_001343466
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Tumorski protein p53-inducibilnog proteina 11 je protein koji je kod ljudi kodiran genom TP53I11.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 189 aminokiselina, а molekulska težina 21.054 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MAAKQPPPLM	KKHSQTDLVS	RLKTRKILGV	GGEDDDGEVH	RSKISQVLGN
EIKFTIREPL	GLRVWQFVSA	VLFSGIAIMA	LAFPDQLYDA	VFDGAQVTSK
TPIRLYGGAL	LSISLIMWNA	LYTAEKVIIR	WTLLTEACYF	GVQFLVVTAT
LAETGLMSLG	ILLLLVSRLL	FVVISIYYYY	QVGRRPKKA

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175274 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068735 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B (Sep 1997). "A model for p53-induced apoptosis". Nature. 389 (6648): 300–5. doi:10.1038/38525. PMID 9305847. S2CID 4429638.
^ "Entrez Gene: TP53I11 tumor protein p53 inducible protein 11".
^ "UniProt, O14683". Pristupljeno 28. 8. 2021.

Dopunska literatura

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Liang XQ, Cao EH, Zhang Y, Qin JF (2004). "P53-induced gene 11 (PIG11) involved in arsenic trioxide-induced apoptosis in human gastric cancer MGC-803 cells". Oncol. Rep. 10 (5): 1265–9. doi:10.3892/or.10.5.1265. PMID 12883691.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Liang XQ, Cao EH, Zhang Y, Qin JF (2004). "A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxide". FEBS Lett. 569 (1–3): 94–8. doi:10.1016/j.febslet.2004.05.057. PMID 15225615. S2CID 25975446.
Fingrut O, Reischer D, Rotem R, et al. (2006). "Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells". Br. J. Pharmacol. 146 (6): 800–8. doi:10.1038/sj.bjp.0706394. PMC 1751213. PMID 16170329.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Xiong XF, Li H, Cao EH (2007). "PIG11 protein binds to DNA in sequence-independent manner in vitro". Biochem. Biophys. Res. Commun. 358 (1): 29–34. doi:10.1016/j.bbrc.2007.04.048. PMID 17482569.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175274 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068735 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9305847-5] Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B (Sep 1997). "A model for p53-induced apoptosis". Nature. 389 (6648): 300–5. doi:10.1038/38525. PMID 9305847. S2CID 4429638.

[entrez-6] "Entrez Gene: TP53I11 tumor protein p53 inducible protein 11".

[UniProt-7] "UniProt, O14683". Pristupljeno 28. 8. 2021.

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