TGF beta-inducibilni jedarni protein 1 jest protein koji je kod ljudi kodiran genom NSA2 sa hromosoma 5.[5][6][7]

TINP1
Identifikatori
AliasiNSA2
Vanjski ID-jeviOMIM: 612497 MGI: 1913883 HomoloGene: 5844 GeneCards: NSA2
Lokacija gena (čovjek)
Hromosom 5 (čovjek)
Hrom.Hromosom 5 (čovjek)[1]
Hromosom 5 (čovjek)
Genomska lokacija za TINP1
Genomska lokacija za TINP1
Bend5q13.3Početak74,766,991 bp[1]
Kraj74,780,113 bp[1]
Lokacija gena (miš)
Hromosom 13 (miš)
Hrom.Hromosom 13 (miš)[2]
Hromosom 13 (miš)
Genomska lokacija za TINP1
Genomska lokacija za TINP1
Bend13|13 D1Početak97,265,932 bp[2]
Kraj97,274,445 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija vezivanje sa RNK
Ćelijska komponenta preribosome, large subunit precursor
jedro
Jedarce
Biološki proces rRNA processing
ribosome biogenesis
maturation of LSU-rRNA
maturation of 5.8S rRNA
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001271665
NM_014886
NM_001364506

NM_021552

RefSeq (bjelančevina)

NP_001258594
NP_055701
NP_001351435

NP_067527

Lokacija (UCSC)Chr 5: 74.77 – 74.78 MbChr 13: 97.27 – 97.27 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 260 aminokiselina, а molekulska težina 30.065 Da.[8]

1020304050
MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLY
HKQRHAEKIQMKKTIKMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAK
VLSNMIKQKRKEKAGKWEVPLPKVRAQGETEVLKVIRTGKRKKKAWKRMV
TKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPILGVK
KNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPEN
DGCINAVLLV

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164346 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060739 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G (januar 2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast. 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID 11124703.
  6. ^ Wu X, Ivanova G, Merup M, Jansson M, Stellan B, Grandér D, Zabarovsky E, Gahrton G, Einhorn S (septembar 1999). "Molecular analysis of the human chromosome 5q13.3 region in patients with hairy cell leukemia and identification of tumor suppressor gene candidates". Genomics. 60 (2): 161–71. doi:10.1006/geno.1999.5911. PMID 10486207.
  7. ^ "Entrez Gene: TINP1 TGF beta-inducible nuclear protein 1".
  8. ^ "UniProt, O95478" (jezik: engleski). Pristupljeno 17. 10. 2021.

Dopunska literatura

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