Timocitno eksprimirani pozitivno selektirano pridruženi protein 1 je protein koji je kod ljudi kodiran genom TESPA1.[4]

TESPA1
Identifikatori
AliasiTESPA1
Vanjski ID-jeviOMIM: 615664 MGI: 1914846 HomoloGene: 106645 GeneCards: TESPA1
Lokacija gena (miš)
Hromosom 10 (miš)
Hrom.Hromosom 10 (miš)[1]
Hromosom 10 (miš)
Genomska lokacija za TESPA1
Genomska lokacija za TESPA1
Bend10|10 D3Početak130,158,739 bp[1]
Kraj130,199,980 bp[1]
Ontologija gena
Molekularna funkcija signaling receptor binding
Ćelijska komponenta COP9 signalosome
endoplasmic reticulum membrane
Endoplazmatski retikulum
membrana
citoplazma
Biološki proces COP9 signalosome assembly
positive regulation of T cell differentiation in thymus
positive regulation of T cell receptor signaling pathway
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001098815
NM_001136030
NM_001261844
NM_014796

NM_183264

RefSeq (bjelančevina)
NP_001092285
NP_001129502
NP_001248773
NP_055611
NP_001338077

NP_001338078
NP_001338079
NP_001338080
NP_001338081
NP_001338082
NP_001338083
NP_001338084

NP_899087

Lokacija (UCSC)n/aChr 10: 130.16 – 130.2 Mb
PubMed pretraga[2][3]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 521 aminokiselina, a molekulska težina 59 213 Da.[5]

1020304050
MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDVPDPEPSSLDD
VFQEGNPINKIEDWLQDCGYSEEGFSEEAGQFIYNGFCSHGTSFEDDLTL
GAEATLLAANGKLFSRSFLETARPCQLLDLGCSLASSSMTGGTNKTSSSI
SEILDKVQEDAEDVLFSLGFGQEDHKDTSRIPARFFTTPSQAKGIDFQLF
LKSQVRRIEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVSKTPVQKFT
PSHMFWNCNHPTDVPSIRILSREPEPQSPRDRLRKAISKMCLYTCPRDRP
PPPHNTPKRNSLDQVVLEVMDKVKEEKQFLQQDSDLGQFSQEDPVPPAEG
KKLPTSPYPCVFCCEEETQQRMSTVLAPSQTLDSNPKVPCCTHSLPIEDP
QWSTDPAQIRRELCSLPATNTETHPAKDETFWKRKSRARKSLFQKNLMGR
KVKSLDLSITQQKWKQSVDRPELRRSLSQQPQDTFDLEEVQSNSEEEQSQ
SRWPSRPRHPHHHQTFAGKDS

Reference

uredi
  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034833 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Entrez Gene: Thymocyte expressed, positive selection associated 1".
  5. ^ "UniProt, A2RU30". Pristupljeno 14. 8. 2021.

Dopunska literatura

uredi
  • Fujimoto T, Matsuzaki H, Tanaka M, Shirasawa S (april 2013). "Tespa1 protein is phosphorylated in response to store-operated calcium entry". Biochemical and Biophysical Research Communications. 434 (1): 162–5. doi:10.1016/j.bbrc.2013.02.128. PMID 23541577.
  • Matsuzaki H, Fujimoto T, Tanaka M, Shirasawa S (april 2013). "Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux". Biochemical and Biophysical Research Communications. 433 (3): 322–6. doi:10.1016/j.bbrc.2013.02.099. PMID 23501103.