Transkripcijski faktor 19 jest protein koji je kod ljudi kodiran genom TCF19.[5][6][7]

TCF19
Identifikatori
AliasiTCF19
Vanjski ID-jeviOMIM: 600912 MGI: 103180 HomoloGene: 5156 GeneCards: TCF19
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za TCF19
Genomska lokacija za TCF19
Bend6p21.33Početak31,158,547 bp[1]
Kraj31,167,159 bp[1]
Lokacija gena (miš)
Hromosom 17 (miš)
Hrom.Hromosom 17 (miš)[2]
Hromosom 17 (miš)
Genomska lokacija za TCF19
Genomska lokacija za TCF19
Bend17|17 B1Početak35,823,631 bp[2]
Kraj35,827,721 bp[2]
Ontologija gena
Molekularna funkcija GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
vezivanje iona metala
GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta jedro
Biološki proces transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
Ćelijska proliferacija
GO:0009373 regulation of transcription, DNA-templated
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
ENSG00000233890
ENSG00000224472
ENSG00000137310
ENSG00000224941
ENSG00000234674
UniProt
RefSeq (mRNK)

NM_001077511
NM_007109
NM_001318908

NM_001163763
NM_001163764
NM_025674

RefSeq (bjelančevina)

NP_001070979
NP_001305837
NP_009040

NP_001157235
NP_001157236
NP_079950

Lokacija (UCSC)Chr 6: 31.16 – 31.17 MbChr 17: 35.82 – 35.83 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 345 aminokiselina, а molekulska težina 37.184 Da.[8]

1020304050
MLPCFQLLRIGGGRGGDLYTFHPPAGAGCTYRLGHRADLCDVALRPQQEP
GLISGIHAELHAEPRGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGD
LLTFGPEGPPGTSPSEFYFMFQQVRVKPQDFAAITIPRSRGEARVGAGFR
PMLPSQGAPQRPLSTFSPAPKATLILNSIGSLSKLRPQPLTFSPSWGGPK
SLPVPAPPGEMGTTPSAPPQRNRRKSVHRVLAELDDESEPPENPPPVLME
PRKKLRVDKAPLTPTGNRRGRPRKYPVSAPMAPPAVGGGEPCAAPCCCLP
QEETVAWVQCDGCDVWFHVACVGCSIQAAREADFRCPGCRAGIQT

Reference

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  1. ^ a b c ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 GRCh38: Ensembl release 89: ENSG00000233890, ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050410 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ku DH, Chang CD, Koniecki J, Cannizzaro LA, Boghosian-Sell L, Alder H, Baserga R (Sep 1991). "A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor". Cell Growth Differ. 2 (4): 179–86. PMID 1868030.
  6. ^ Krishnan BR, Jamry I, Chaplin DD (Apr 1996). "Feature mapping of the HLA class I region: localization of the POU5F1 and TCF19 genes". Genomics. 30 (1): 53–8. doi:10.1006/geno.1995.0008. PMID 8595903.
  7. ^ "Entrez Gene: TCF19 transcription factor 19 (SC1)".
  8. ^ "UniProt, Q9Y242" (jezik: engleski). Pristupljeno 5. 10. 2021.

Dopunska literatura

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